Three-dimensional Cone-beam Computed Tomography for Diagnosis of Keratocystic Odontogenic Tumours; Evaluation of Four Cases

Overview

Journal Med Oral Patol Oral Cir Bucal

Specialty Dentistry

Date 2012 May 3

PMID 22549670

Citations 8

Authors

Hulya Kocak-Berberoglu

Sirmahan Cakarer

Amila Brkic

Banu Gurkan-Koseoglu

Baris Altug-Aydil

Cengizhan Keskin

Affiliations

Soon will be listed here.

Abstract

The keratocystic odontogenic tumour (KCOT), formerly known as the odontogenic keratocyst (OKC) is a benign intraosseous lesion that derives from remnants of the dental lamina. Due to its characteristics, clinical and histopathological features and various treatment approaches, this pathology is different comparing with other odontogenic cysts. Radiographically the KCOT appears as well-defined unilocular or multilocular radiolucency with thin radiopaque borders. In most cases, conventional radiographic imaging, such as panoramic views and intraoral periapical films, are adequate to determine the location and estimate the size of an KCOT. However, the clinical use for cone-beam computed tomography (CBCT) in oral and maxillofacial surgery increases and provides additional information about the contents and borders of the large lesions. In the present cases, the diagnostic performances of CBCT versus panoramic radiograph for four KCOTs were evaluated. It was concluded that appearance of lesions in the maxillofacial region could be better documented in the correct dimensions by CBCT versus panoramic radiograph.

Citing Articles

The Utility of Cone Beam Computed Tomography Scans in Diagnosing and Treating Anterior Lesions of the Maxilla and Mandible.

Muttanahally K, Sheppard S, Yadav S, Tadinada A Cureus. 2024; 16(1):e52804.

PMID: 38389599 PMC: 10883409. DOI: 10.7759/cureus.52804.

An Insight Into the Effect of Odontogenic Keratocysts on Surrounding Structures: Cone-Beam Computed Tomography-Based Analysis of Cases.

Ac V, Parihar A, Saxena A Cureus. 2023; 15(6):e40488.

PMID: 37461795 PMC: 10349913. DOI: 10.7759/cureus.40488.

Three-dimensional radiographic features of ameloblastoma and cystic lesions in the maxilla.

Meng Y, Zhao Y, Zhang Y, Liu D, Gao Y Dentomaxillofac Radiol. 2019; 48(6):20190066.

PMID: 31124699 PMC: 6747442. DOI: 10.1259/dmfr.20190066.

Evaluation of mandibular odontogenic keratocyst and ameloblastoma by panoramic radiograph and computed tomography.

Alves D, Mesquita Tuji F, Alves F, Rocha A, Santos-Silva A, Vargas P Dentomaxillofac Radiol. 2018; 47(7):20170288.

PMID: 29791200 PMC: 6196060. DOI: 10.1259/dmfr.20170288.

Evaluation of keratocystic odontogenic tumors using cone beam computed tomography.

Gumusok M, Toraman Alkurt M, Museyibov F, Ucok O J Istanb Univ Fac Dent. 2017; 50(3):32-37.

PMID: 28955573 PMC: 5573512. DOI: 10.17096/jiufd.58691.

References

Chau A, Fung K . Comparison of radiation dose for implant imaging using conventional spiral tomography, computed tomography, and cone-beam computed tomography. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009; 107(4):559-65. DOI: 10.1016/j.tripleo.2008.11.009. View

Boeddinghaus R, Whyte A . Current concepts in maxillofacial imaging. Eur J Radiol. 2007; 66(3):396-418. DOI: 10.1016/j.ejrad.2007.11.019. View

Madras J, Lapointe H . Keratocystic odontogenic tumour: reclassification of the odontogenic keratocyst from cyst to tumour. J Can Dent Assoc. 2008; 74(2):165-165h. View

Agaram N, Collins B, Barnes L, Lomago D, Aldeeb D, Swalsky P . Molecular analysis to demonstrate that odontogenic keratocysts are neoplastic. Arch Pathol Lab Med. 2004; 128(3):313-7. DOI: 10.5858/2004-128-313-MATDTO. View

Myoung H, Hong S, Hong S, Lee J, Lim C, Choung P . Odontogenic keratocyst: Review of 256 cases for recurrence and clinicopathologic parameters. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001; 91(3):328-33. DOI: 10.1067/moe.2001.113109. View

Munk P, Lee M, Janzen D, Poon P, Logan P, Connell D . Introduction to panoramic dental radiography in oncologic practice. AJR Am J Roentgenol. 1997; 168(4):939-43. DOI: 10.2214/ajr.168.4.9124144. View

Mateus G, Lanza G, de Moura P, Marigo H, Horta M . Cell proliferation and apoptosis in keratocystic odontogenic tumors. Med Oral Patol Oral Cir Bucal. 2008; 13(11):E697-702. View

Scarfe W, Farman A, Sukovic P . Clinical applications of cone-beam computed tomography in dental practice. J Can Dent Assoc. 2006; 72(1):75-80. View

de Vos W, Casselman J, Swennen G . Cone-beam computerized tomography (CBCT) imaging of the oral and maxillofacial region: a systematic review of the literature. Int J Oral Maxillofac Surg. 2009; 38(6):609-25. DOI: 10.1016/j.ijom.2009.02.028. View

10.

Yonetsu K, Bianchi J, Troulis M, Curtin H . Unusual CT appearance in an odontogenic keratocyst of the mandible: case report. AJNR Am J Neuroradiol. 2001; 22(10):1887-9. PMC: 7973825. View

11.

Sukovic P . Cone beam computed tomography in craniofacial imaging. Orthod Craniofac Res. 2003; 6 Suppl 1:31-6. DOI: 10.1034/j.1600-0544.2003.259.x. View

12.

Marmulla R, Wortche R, Muhling J, Hassfeld S . Geometric accuracy of the NewTom 9000 Cone Beam CT. Dentomaxillofac Radiol. 2005; 34(1):28-31. DOI: 10.1259/dmfr/31342245. View

13.

Loubele M, Maes F, Schutyser F, Marchal G, Jacobs R, Suetens P . Assessment of bone segmentation quality of cone-beam CT versus multislice spiral CT: a pilot study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006; 102(2):225-34. DOI: 10.1016/j.tripleo.2005.10.039. View

14.

Zecha J, Amaral Mendes R, Lindeboom V, van der Waal I . Recurrence rate of keratocystic odontogenic tumor after conservative surgical treatment without adjunctive therapies - A 35-year single institution experience. Oral Oncol. 2010; 46(10):740-2. DOI: 10.1016/j.oraloncology.2010.07.004. View

15.

Grasmuck E, Nelson B . Keratocystic odontogenic tumor. Head Neck Pathol. 2010; 4(1):94-6. PMC: 2825523. DOI: 10.1007/s12105-009-0146-x. View

16.

Amaral Mendes R, Carvalho J, van der Waal I . Characterization and management of the keratocystic odontogenic tumor in relation to its histopathological and biological features. Oral Oncol. 2010; 46(4):219-25. DOI: 10.1016/j.oraloncology.2010.01.012. View

17.

Apajalahti S, Hagstrom J, Lindqvist C, Suomalainen A . Computerized tomography findings and recurrence of keratocystic odontogenic tumor of the mandible and maxillofacial region in a series of 46 patients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010; 111(3):e29-37. DOI: 10.1016/j.tripleo.2010.10.010. View

18.

Senguven B, Oygur T . Investigation of interleukin-1 alpha and interleukin-6 expression and interleukin-1 alpha gene polymorphism in keratocystic odontogenic tumors and ameloblastomas. Med Oral Patol Oral Cir Bucal. 2011; 16(4):e467-72. View

19.

Cakur B, Miloglu O, Yolcu U, Goregen M, Gursan N . Keratocystic odontogenic tumor invading the right maxillary sinus: a case report. J Oral Sci. 2008; 50(3):345-9. DOI: 10.2334/josnusd.50.345. View