A Naturally Occurring Epizootic of Simian Agent 8 in the Baboon

Overview

Journal Lab Anim Sci

Specialty Veterinary Medicine

Date 1988 Aug 1

PMID 2846956

Citations 14

Authors

J L Levin

J K Hilliard

S L Lipper

T M Butler

W J Goodwin

Affiliations

Soon will be listed here.

Abstract

An epizootic of genital lesions was observed on baboons (four Papio sub-species) housed in two different outdoor breeding corrals. Serological analysis revealed strong prevalence of antibodies to Simian Agent 8 (SA8). This herpesvirus was subsequently recovered from skin lesions and identified by restriction endonuclease digestion of infected cell DNA. Observations of lesion type, frequency and location were suggestive of venereal transmission. The remarkable similarity between infection resulting from SA8 in baboons and herpes simplex virus in man suggests that the baboon is an excellent model in which to study genital herpes virus transmission and infection.

Citing Articles

A Fosmid-Based System for the Generation of Recombinant Cercopithecine Alphaherpesvirus 2 Encoding Reporter Genes.

Chukhno E, Gartner S, Siregar A, Mehr A, Wende M, Petkov S Viruses. 2019; 11(11).

PMID: 31694178 PMC: 6893520. DOI: 10.3390/v11111026.

Understanding Primate Herpesviruses.

Eberle R, Jones-Engel L J Emerg Dis Virol. 2018; 3(1).

PMID: 29607423 PMC: 5878061. DOI: 10.16966/2473-1846.127.

Papiine herpesvirus 2 as a predictive model for drug sensitivity of Macacine herpesvirus 1 (monkey B virus).

Brush L, Black D, McCormack K, Maxwell L, Wright G, Ritchey J Comp Med. 2014; 64(5):386-93.

PMID: 25402179 PMC: 4236787.

Monkey B virus (Cercopithecine herpesvirus 1).

Elmore D, Eberle R Comp Med. 2009; 58(1):11-21.

PMID: 19793452 PMC: 2703160.

Nonhuman primate dermatology: a literature review.

Bernstein J, Didier P Vet Dermatol. 2009; 20(3):145-56.

PMID: 19490576 PMC: 4416230. DOI: 10.1111/j.1365-3164.2009.00742.x.