Maturing of the Nuclear Receptor Family

Overview

Journal J Clin Invest

Specialty General Medicine

Date 2017 Apr 4

PMID 28368290

Citations 38

Authors

Mitchell A Lazar

Affiliations

Soon will be listed here.

Abstract

Members of the nuclear receptor (NR) superfamily of ligand-regulated transcription factors play important roles in reproduction, development, and physiology. In humans, genetic mutations in NRs are causes of rare diseases, while hormones and drugs that target NRs are in widespread therapeutic use. The present issue of the JCI includes a series of Review articles focused on specific NRs and their wide range of biological functions. Here I reflect on the past, present, and potential future highlights of research on the NR superfamily.

Citing Articles

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