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Prosthetic Joint Infection-a Devastating Complication of Hemiarthroplasty for Hip Fracture

Overview
Journal Acta Orthop
Specialty Orthopedics
Date 2017 Mar 9
PMID 28271919
Citations 24
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Abstract

Background and purpose - Hemiarthroplasty is the most common treatment in elderly patients with displaced femoral neck fracture. Prosthetic joint infection (PJI) is a feared complication. The infection rate varies in the literature, and there are limited descriptive data available. We investigated the characteristics and outcome of PJI following hemiarthroplasty over a 15-year period. Patients and methods - Patients with PJI were identified among 519 patients treated with hemiarthroplasty for a femoral neck fracture at Oslo University Hospital between 1998 and 2012. We used prospectively registered data from previous studies, and recorded additional data from the patients' charts when needed. Results - Of the 519 patients, we identified 37 patients (6%) with early PJI. 20 of these 37 patients became free of infection. Soft tissue debridement and retention of implant was performed in 35 patients, 15 of whom became free of infection with an intact arthroplasty. The 1-year mortality rate was 15/37. We found an association between 1-year mortality and treatment failure (p = 0.001). Staphylococcus aureus and polymicrobial infection were the most common microbiological findings, each accounting for 14 of the 37 infections. Enterococcus spp. was found in 9 infections, 8 of which were polymicrobial. There was an association between polymicrobial infection and treatment failure, and between polymicrobial infection and 1-year mortality. Interpretation - PJI following hemiarthroplasty due to femoral neck fracture is a devastating complication in the elderly. We found a high rate of polymicrobial PJIs frequently including Enterococcus spp, which is different from what is common in PJI after elective total hip arthroplasty.

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References
1.
Meehan J, Jamali A, Nguyen H . Prophylactic antibiotics in hip and knee arthroplasty. J Bone Joint Surg Am. 2009; 91(10):2480-90. DOI: 10.2106/JBJS.H.01219. View

2.
Malhas A, Lawton R, Reidy M, Nathwani D, Clift B . Causative organisms in revision total hip & knee arthroplasty for infection: Increasing multi-antibiotic resistance in coagulase-negative Staphylococcus and the implications for antibiotic prophylaxis. Surgeon. 2014; 13(5):250-5. DOI: 10.1016/j.surge.2014.04.002. View

3.
Frihagen F, Nordsletten L, Madsen J . Hemiarthroplasty or internal fixation for intracapsular displaced femoral neck fractures: randomised controlled trial. BMJ. 2007; 335(7632):1251-4. PMC: 2137068. DOI: 10.1136/bmj.39399.456551.25. View

4.
Soriano A, Popescu D, Garcia S, Bori G, Martinez J, Balasso V . Usefulness of teicoplanin for preventing methicillin-resistant Staphylococcus aureus infections in orthopedic surgery. Eur J Clin Microbiol Infect Dis. 2006; 25(1):35-8. DOI: 10.1007/s10096-005-0073-z. View

5.
Rasouli M, Tripathi M, Kenyon R, Wetters N, Della Valle C, Parvizi J . Low rate of infection control in enterococcal periprosthetic joint infections. Clin Orthop Relat Res. 2012; 470(10):2708-16. PMC: 3442013. DOI: 10.1007/s11999-012-2374-8. View