Using Epigenomic Data to Inform Genome-wide Association Studies of Bone Mineral Density
Overview
Overview
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
Citing Articles
High-Resolution Regulatory Maps Connect Vascular Risk Variants to Disease-Related Pathways.
Akerborg O, Spalinskas R, Pradhananga S, Anil A, Hojer P, Poujade F Circ Genom Precis Med. 2019; 12(3):e002353.
PMID: 30786239 PMC: 8104016. DOI: 10.1161/CIRCGEN.118.002353.
Epigenomic data facilitate genetic studies for osteoporosis in post-GWAS era.
Guo Y, Dong S, Yang T Ann Transl Med. 2017; 5(4):93.
PMID: 28275638 PMC: 5337227. DOI: 10.21037/atm.2017.02.08.
References
1.
Styrkarsdottir U, Thorleifsson G, Gudjonsson S, Sigurdsson A, Center J, Lee S
. Sequence variants in the PTCH1 gene associate with spine bone mineral density and osteoporotic fractures. Nat Commun. 2016; 7:10129.
PMC: 4729819.
DOI: 10.1038/ncomms10129.
View
2.
Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A
. Integrative analysis of 111 reference human epigenomes. Nature. 2015; 518(7539):317-30.
PMC: 4530010.
DOI: 10.1038/nature14248.
View
3.
Koller D, Ichikawa S, Lai D, Padgett L, Doheny K, Pugh E
. Genome-wide association study of bone mineral density in premenopausal European-American women and replication in African-American women. J Clin Endocrinol Metab. 2010; 95(4):1802-9.
PMC: 2853986.
DOI: 10.1210/jc.2009-1903.
View
4.
Welter D, MacArthur J, Morales J, Burdett T, Hall P, Junkins H
. The NHGRI GWAS Catalog, a curated resource of SNP-trait associations. Nucleic Acids Res. 2013; 42(Database issue):D1001-6.
PMC: 3965119.
DOI: 10.1093/nar/gkt1229.
View
5.
. An integrated encyclopedia of DNA elements in the human genome. Nature. 2012; 489(7414):57-74.
PMC: 3439153.
DOI: 10.1038/nature11247.
View