Modelling Mitral Valvular Dynamics-current Trend and Future Directions

Overview

Journal Int J Numer Method Biomed Eng

Publisher Wiley

Specialties Biomedical Engineering
Public Health

Date 2016 Dec 10

PMID 27935265

Citations 15

Authors

Hao Gao

Nan Qi

Liuyang Feng

Xingshuang Ma

Mark Danton

Colin Berry

Xiaoyu Luo

Affiliations

Soon will be listed here.

Abstract

Dysfunction of mitral valve causes morbidity and premature mortality and remains a leading medical problem worldwide. Computational modelling aims to understand the biomechanics of human mitral valve and could lead to the development of new treatment, prevention and diagnosis of mitral valve diseases. Compared with the aortic valve, the mitral valve has been much less studied owing to its highly complex structure and strong interaction with the blood flow and the ventricles. However, the interest in mitral valve modelling is growing, and the sophistication level is increasing with the advanced development of computational technology and imaging tools. This review summarises the state-of-the-art modelling of the mitral valve, including static and dynamics models, models with fluid-structure interaction, and models with the left ventricle interaction. Challenges and future directions are also discussed.

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