Transmission of Viruses Via Our Microbiomes

Overview

Journal Microbiome

Publisher Biomed Central

Specialties Genetics
Microbiology

Date 2016 Dec 4

PMID 27912785

Citations 33

Authors

Melissa Ly

Marcus B Jones

Shira R Abeles

Tasha M Santiago-Rodriguez

Jonathan Gao

Ivan C Chan

Chandrabali Ghose

David T Pride

Affiliations

Soon will be listed here.

Abstract

Background: Bacteria inhabiting the human body have important roles in a number of physiological processes and are known to be shared amongst genetically-related individuals. Far less is known about viruses inhabiting the human body, but their ecology suggests they may be shared between close contacts.

Results: Here, we report the ecology of viruses in the guts and mouths of a cohort and demonstrate that substantial numbers of gut and oral viruses were shared amongst genetically unrelated, cohabitating individuals. Most of these viruses were bacteriophages, and each individual had distinct oral and gut viral ecology from their housemates despite the fact that some of their bacteriophages were shared. The distribution of bacteriophages over time within households indicated that they were frequently transmitted between the microbiomes of household contacts.

Conclusions: Because bacteriophages may shape human oral and gut bacterial ecology, their transmission to household contacts suggests they could have substantial roles in shaping the microbiota within a household.

Citing Articles

A review and new perspective on oral bacteriophages: manifestations in the ecology of oral diseases.

Guo X, Wang X, Shi J, Ren J, Zeng J, Li J J Oral Microbiol. 2024; 16(1):2344272.

PMID: 38698893 PMC: 11064738. DOI: 10.1080/20002297.2024.2344272.

Discovering and exploring the hidden diversity of human gut viruses using highly enriched virome samples.

Zolfo M, Silverj A, Blanco-Miguez A, Manghi P, Rota-Stabelli O, Heidrich V bioRxiv. 2024; .

PMID: 38464031 PMC: 10925137. DOI: 10.1101/2024.02.19.580813.

Characteristics of intestinal bacteriophages and their relationship with Bacteria and serum metabolites during quail sexual maturity transition.

Xiong X, Gong J, Lu T, Yuan L, Lan Y, Tu X BMC Vet Res. 2024; 20(1):93.

PMID: 38459523 PMC: 10921806. DOI: 10.1186/s12917-024-03945-9.

Oral bacteriophages: metagenomic clues to interpret microbiomes.

Banar M, Rokaya D, Azizian R, Khurshid Z, Banakar M PeerJ. 2024; 12:e16947.

PMID: 38406289 PMC: 10885796. DOI: 10.7717/peerj.16947.

Exploring the Human Virome: Composition, Dynamics, and Implications for Health and Disease.

Bhagchandani T, Nikita , Verma A, Tandon R Curr Microbiol. 2023; 81(1):16.

PMID: 38006423 DOI: 10.1007/s00284-023-03537-0.

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