Motion-robust Cardiac B1+ Mapping at 3T Using Interleaved Bloch-siegert Shifts

Overview

Journal Magn Reson Med

Publisher Wiley

Specialty Radiology

Date 2016 Sep 8

PMID 27599782

Citations 9

Authors

Sebastian Weingartner

Fabian Zimmer

Gregory J Metzger

Kamil Ugurbil

Pierre-Francois Van de Moortele

Mehmet Akcakaya

Affiliations

Soon will be listed here.

Abstract

Purpose: To develop and evaluate a robust motion-insensitive Bloch-Siegert shift based B1+ mapping method in the heart.

Methods: Cardiac Bloch-Siegert B1+ mapping was performed with interleaved positive and negative off-resonance shifts and diastolic spoiled gradient echo imaging in 12 heartbeats. Numerical simulations were performed to study the impact of respiratory motion. The method was compared with three-dimensional (3D) actual flip angle imaging (AFI) and two-dimensional (2D) saturated double angle method (SDAM) in phantom scans. Cardiac B1+ maps of three different views were acquired in six healthy volunteers using Bloch-Siegert and SDAM during breath-hold and free breathing. In vivo maps were evaluated for inter-view consistency using the correlation coefficients of the B1+ profiles along the lines of intersection between the views.

Results: For the Bloch-Siegert sequence, numerical simulations indicated high similarity between breath-hold and free breathing scans, and phantom results indicated low deviation from the 3D AFI reference (normalized root mean square error [NRMSE] = 2.0%). Increased deviation was observed with 2D SDAM (NRMSE = 5.0%) due to underestimation caused by imperfect excitation slice profiles. Breath-hold and free breathing Bloch-Siegert in vivo B1+ maps were visually comparable with no significant difference in the inter-view consistency (P > 0.36). SDAM showed strongly impaired B1+ map quality during free breathing. Inter-view consistency was significantly lower than with the Bloch-Siegert method (breath-hold: P = 0.014, free breathing: P < 0.0001).

Conclusion: The proposed interleaved Bloch-Siegert sequence enables cardiac B1+ mapping with improved inter-view consistency and high resilience to respiratory motion. Magn Reson Med 78:670-677, 2017. © 2016 International Society for Magnetic Resonance in Medicine.

Citing Articles

Feasibility of relaxation along a fictitious field in the 2nd rotating frame (T) mapping in the human myocardium at 3 T.

Tourais J, Bozic-Iven M, Zhao Y, Tao Q, Pierce I, Nitsche C Front Cardiovasc Med. 2024; 11:1373240.

PMID: 39697300 PMC: 11652659. DOI: 10.3389/fcvm.2024.1373240.

Improved reproducibility for myocardial ASL: Impact of physiological and acquisition parameters.

Bozic-Iven M, Rapacchi S, Tao Q, Pierce I, Thornton G, Nitsche C Magn Reson Med. 2023; 91(1):118-132.

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Robust cardiac mapping at 3T using adiabatic spin-lock preparations.

Coletti C, Fotaki A, Tourais J, Zhao Y, Van De Steeg-Henzen C, Akcakaya M Magn Reson Med. 2023; 90(4):1363-1379.

PMID: 37246420 PMC: 10984724. DOI: 10.1002/mrm.29713.

Rapid 3D absolute B mapping using a sandwiched train presaturated TurboFLASH sequence at 7 T for the brain and heart.

Kent J, Dragonu I, Valkovic L, Hess A Magn Reson Med. 2022; 89(3):964-976.

PMID: 36336893 PMC: 10099228. DOI: 10.1002/mrm.29497.

Free-breathing abdominal T mapping using an optimized MR fingerprinting sequence.

Riel M, Yu Z, Hodono S, Xia D, Chandarana H, Fujimoto K NMR Biomed. 2021; 34(7):e4531.

PMID: 33902155 PMC: 8218311. DOI: 10.1002/nbm.4531.

References

Hamlin S, Henry T, Little B, Lerakis S, Stillman A . Mapping the future of cardiac MR imaging: case-based review of T1 and T2 mapping techniques. Radiographics. 2014; 34(6):1594-611. DOI: 10.1148/rg.346140030. View

Cameron D, Siddiqi N, Neil C, Jagpal B, Bruce M, Higgins D . T₁ mapping for assessment of myocardial injury and microvascular obstruction at one week post myocardial infarction. Eur J Radiol. 2015; 85(1):279-285. DOI: 10.1016/j.ejrad.2015.10.008. View

Akcakaya M, Weingartner S, Basha T, Roujol S, Bellm S, Nezafat R . Joint myocardial T1 and T2 mapping using a combination of saturation recovery and T2 -preparation. Magn Reson Med. 2015; 76(3):888-96. PMC: 4811754. DOI: 10.1002/mrm.25975. View

Yarnykh V . Actual flip-angle imaging in the pulsed steady state: a method for rapid three-dimensional mapping of the transmitted radiofrequency field. Magn Reson Med. 2006; 57(1):192-200. DOI: 10.1002/mrm.21120. View

Sled J, Pike G . Correction for B(1) and B(0) variations in quantitative T(2) measurements using MRI. Magn Reson Med. 2000; 43(4):589-93. DOI: 10.1002/(sici)1522-2594(200004)43:4<589::aid-mrm14>3.0.co;2-2. View

Snyder C, Delabarre L, Metzger G, Van de Moortele P, Akgun C, Ugurbil K . Initial results of cardiac imaging at 7 Tesla. Magn Reson Med. 2008; 61(3):517-24. PMC: 2939145. DOI: 10.1002/mrm.21895. View

Pelgrim G, Handayani A, Dijkstra H, Prakken N, Slart R, Oudkerk M . Quantitative Myocardial Perfusion with Dynamic Contrast-Enhanced Imaging in MRI and CT: Theoretical Models and Current Implementation. Biomed Res Int. 2016; 2016:1734190. PMC: 4806267. DOI: 10.1155/2016/1734190. View

Morrell G, Schabel M . An analysis of the accuracy of magnetic resonance flip angle measurement methods. Phys Med Biol. 2010; 55(20):6157-74. DOI: 10.1088/0031-9155/55/20/008. View

Saranathan M, Khalighi M, Glover G, Pandit P, Rutt B . Efficient Bloch-Siegert B1 (+) mapping using spiral and echo-planar readouts. Magn Reson Med. 2013; 70(6):1669-73. PMC: 3657582. DOI: 10.1002/mrm.24599. View

10.

Coolen B, Geelen T, Paulis L, Nauerth A, Nicolay K, Strijkers G . Three-dimensional T1 mapping of the mouse heart using variable flip angle steady-state MR imaging. NMR Biomed. 2010; 24(2):154-62. DOI: 10.1002/nbm.1566. View

11.

Didier D, Ratib O, Lerch R, Friedli B . Detection and quantification of valvular heart disease with dynamic cardiac MR imaging. Radiographics. 2000; 20(5):1279-99; discussion 1299-301. DOI: 10.1148/radiographics.20.5.g00jl111279. View

12.

Salerno M, Kramer C . Advances in parametric mapping with CMR imaging. JACC Cardiovasc Imaging. 2013; 6(7):806-22. PMC: 4073213. DOI: 10.1016/j.jcmg.2013.05.005. View

13.

Pohmann R, Scheffler K . A theoretical and experimental comparison of different techniques for B₁ mapping at very high fields. NMR Biomed. 2012; 26(3):265-75. DOI: 10.1002/nbm.2844. View

14.

Lau A, Chen A, Cunningham C . Integrated Bloch-Siegert B₁ mapping and multislice imaging of hyperpolarized ¹³C pyruvate and bicarbonate in the heart. Magn Reson Med. 2011; 67(1):62-71. DOI: 10.1002/mrm.22977. View

15.

Lutti A, Stadler J, Josephs O, Windischberger C, Speck O, Bernarding J . Robust and fast whole brain mapping of the RF transmit field B1 at 7T. PLoS One. 2012; 7(3):e32379. PMC: 3299646. DOI: 10.1371/journal.pone.0032379. View

16.

Ibrahim T, Lee R, Baertlein B, Abduljalil A, Zhu H, Robitaille P . Effect of RF coil excitation on field inhomogeneity at ultra high fields: a field optimized TEM resonator. Magn Reson Imaging. 2002; 19(10):1339-47. DOI: 10.1016/s0730-725x(01)00404-0. View

17.

Fontana M, Banypersad S, Treibel T, Maestrini V, Sado D, White S . Native T1 mapping in transthyretin amyloidosis. JACC Cardiovasc Imaging. 2014; 7(2):157-65. DOI: 10.1016/j.jcmg.2013.10.008. View

18.

Mao W, Smith M, Collins C . Exploring the limits of RF shimming for high-field MRI of the human head. Magn Reson Med. 2006; 56(4):918-22. PMC: 4040521. DOI: 10.1002/mrm.21013. View

19.

Kim R, Shah D, Judd R . How we perform delayed enhancement imaging. J Cardiovasc Magn Reson. 2003; 5(3):505-14. DOI: 10.1081/jcmr-120022267. View

20.

Weingartner S, Akcakaya M, Roujol S, Basha T, Tschabrunn C, Berg S . Free-breathing combined three-dimensional phase sensitive late gadolinium enhancement and T1 mapping for myocardial tissue characterization. Magn Reson Med. 2014; 74(4):1032-41. PMC: 4400224. DOI: 10.1002/mrm.25495. View