Higher-order Organization of Complex Networks
Affiliations
Networks are a fundamental tool for understanding and modeling complex systems in physics, biology, neuroscience, engineering, and social science. Many networks are known to exhibit rich, lower-order connectivity patterns that can be captured at the level of individual nodes and edges. However, higher-order organization of complex networks--at the level of small network subgraphs--remains largely unknown. Here, we develop a generalized framework for clustering networks on the basis of higher-order connectivity patterns. This framework provides mathematical guarantees on the optimality of obtained clusters and scales to networks with billions of edges. The framework reveals higher-order organization in a number of networks, including information propagation units in neuronal networks and hub structure in transportation networks. Results show that networks exhibit rich higher-order organizational structures that are exposed by clustering based on higher-order connectivity patterns.
Resolving discrepancies between chimeric and multiplicative measures of higher-order epistasis.
Chitra U, Arnold B, Raphael B Nat Commun. 2025; 16(1):1711.
PMID: 39962081 PMC: 11833126. DOI: 10.1038/s41467-025-56986-5.
Coarse-graining network flow through statistical physics and machine learning.
Zhang Z, Ghavasieh A, Zhang J, De Domenico M Nat Commun. 2025; 16(1):1605.
PMID: 39948344 PMC: 11825948. DOI: 10.1038/s41467-025-56034-2.
CompLex: Legal systems through the lens of complexity science.
Vivo P, Katz D, Ruhl J Europhys Lett. 2025; 149(2):22001.
PMID: 39866179 PMC: 7617345. DOI: 10.1209/0295-5075/ad99fc.
Su X, Hu P, Li D, Zhao B, Niu Z, Herget T Nat Biomed Eng. 2025; .
PMID: 39789329 DOI: 10.1038/s41551-024-01312-5.
Peng Y, Xia J, Liu D, Liu M, Xiao L, Shi B Sci Rep. 2025; 15(1):805.
PMID: 39755762 PMC: 11700118. DOI: 10.1038/s41598-024-84816-z.