A Maize Death Acid, 10-oxo-11-phytoenoic Acid, is the Predominant Cyclopentenone Signal Present During Multiple Stress and Developmental Conditions

Overview

Journal Plant Signal Behav

Specialty Biology

Date 2015 Dec 17

PMID 26669723

Citations 12

Authors

Shawn A Christensen

Alisa Huffaker

Charles T Hunter

Hans T Alborn

Eric A Schmelz

Affiliations

Soon will be listed here.

Abstract

Recently we investigated the function of the 9-lipoxygenase (LOX) derived cyclopentenones 10-oxo-11-phytoenoic acid (10-OPEA) and 10-oxo-11,15-phytodienoic acid (10-OPDA) and identified their C-14 and C-12 derivatives. 10-OPEA accumulation is elicited by fungal and insect attack and acts as a strong inhibitor of microbial and herbivore growth. Although structurally similar, comparative analyses between 10-OPEA and its 13-LOX analog 12-oxo-phytodienoic acid (12-OPDA) demonstrate specificity in transcript accumulation linked to detoxification, secondary metabolism, jasmonate regulation, and protease inhibition. As a potent cell death signal, 10-OPEA activates cysteine protease activity leading to ion leakage and apoptotic-like DNA fragmentation. In this study we further elucidate the distribution, abundance, and functional roles of 10-OPEA, 10-OPDA, and 12-OPDA, in diverse organs under pathogen- and insect-related stress.

Citing Articles

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