Molecular Characterization of Novel Reassortant H6N2 Subtype Avian Influenza Viruses Isolated from Poultry in Eastern China, in 2014

Overview

Journal Infect Genet Evol

Specialties Biology
Genetics
Infectious Diseases

Date 2015 Sep 6

PMID 26341862

Citations 6

Authors

Haibo Wu

Xiuming Peng

Xiaorong Peng

Linfang Cheng

Nanping Wu

Affiliations

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Abstract

During the surveillance for avian influenza viruses (AIVs) in live poultry markets in Eastern China, in 2014, seven H6N2 AIVs were isolated from poultry. Phylogenetic analysis showed that these strains received their genes from H6, H3, and H9 AIVs of poultry in China. These strains were found to demonstrate moderate pathogenicity in mice, and were able to replicate in mice without prior adaptation. Considering that novel reassorted H6N2 viruses were isolated from poultry in this study, it is possible that these chickens and ducks play an important role in the generation of novel reassorted H6N2 AIVs.

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