Autologous Matrix-Induced Chondrogenesis (AMIC): Combining Microfracturing and a Collagen I/III Matrix for Articular Cartilage Resurfacing

Overview

Journal Cartilage

Date 2015 Jun 13

PMID 26069536

Citations 41

Authors

J P Benthien

P Behrens

Affiliations

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Abstract

Options for the treatment of cartilage defects include chondral resurfacing with abrasion, debridement, autologous chondrocyte transplantation (ACT), matrix-induced chondrocyte transplantation (MACI), or osteochondral autologous transplantation (OATS). This article describes the new method of autologous matrix-induced chondrogenesis (AMIC), a 1-step procedure combining subchondral microfracture with the fixation of a collagen I/III membrane by a partially autologous fibrin glue. Indications and contraindications are provided; a technical note is given. This method is primarily applied in osteochondral lesions of the knee and ankle joints; other joints may qualify.

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