Articular and Artificial Cartilage, Characteristics, Properties and Testing Approaches-A Review
Overview
Affiliations
The design and manufacture of artificial tissue for knee joints have been highlighted recently among researchers which necessitates an apt approach for its assessment. Even though most re-searches have focused on specific mechanical or tribological tests, other aspects have remained underexplored. In this review, elemental keys for design and testing artificial cartilage are dis-cussed and advanced methods addressed. Articular cartilage structure, its compositions in load-bearing and tribological properties of hydrogels, mechanical properties, test approaches and wear mechanisms are discussed. Bilayer hydrogels as a niche in tissue artificialization are presented, and recent gaps are assessed.
Synthesis of PVA-Based Hydrogels for Biomedical Applications: Recent Trends and Advances.
Khan M, Rumon M Gels. 2025; 11(2).
PMID: 39996631 PMC: 11854265. DOI: 10.3390/gels11020088.
Advancements in hydrogel design for articular cartilage regeneration: A comprehensive review.
Hashemi-Afzal F, Fallahi H, Bagheri F, Collins M, Baghaban Eslaminejad M, Seitz H Bioact Mater. 2024; 43:1-31.
PMID: 39318636 PMC: 11418067. DOI: 10.1016/j.bioactmat.2024.09.005.
Krakowski P, Rejniak A, Sobczyk J, Karpinski R Healthcare (Basel). 2024; 12(16).
PMID: 39201206 PMC: 11353818. DOI: 10.3390/healthcare12161648.
Tribomechanical Properties of PVA/Nomex Composite Hydrogels for Articular Cartilage Repair.
Santos F, Marto-Costa C, Branco A, Oliveira A, Galhano Dos Santos R, Salema-Oom M Gels. 2024; 10(8).
PMID: 39195043 PMC: 11354222. DOI: 10.3390/gels10080514.
Lu P, Ruan D, Huang M, Tian M, Zhu K, Gan Z Signal Transduct Target Ther. 2024; 9(1):166.
PMID: 38945949 PMC: 11214942. DOI: 10.1038/s41392-024-01852-x.