The Canadian Systemic Sclerosis Oral Health Study IV: Oral Radiographic Manifestations in Systemic Sclerosis Compared with the General Population

Overview

Journal Oral Surg Oral Med Oral Pathol Oral Radiol

Publisher Elsevier

Specialties Dentistry
General Surgery

Date 2015 May 12

PMID 25959972

Citations 19

Authors

Marie Dagenais

David MacDonald

Murray Baron

Marie Hudson

Solene Tatibouet

Russell Steele

Sabrina Gravel

Shrisha Mohit

Tarek El Sayegh

Janet Pope

Audrey Fontaine

Ariel Masseto

Debora Matthews

Evelyn Sutton

Norman Thie

Niall Jones

Maria Copete

Dean Kolbinson

Janet Markland

Getulio Nogueira-Filho

David Robinson

Mervyn Gornitsky

Affiliations

Soon will be listed here.

Abstract

Objective: The aim of this study was to compare oral radiologic abnormalities associated with systemic sclerosis (SSc) against abnormalities in the general population.

Study Design: Patients with SSc and healthy controls were enrolled in a multi-site cross-sectional study. Included in the radiology examination were a panoramic radiograph, four bitewings, and an anterior mandibular periapical radiograph. Radiographs were evaluated by two oral and maxillofacial radiologists tested for interobserver and intraobserver reliability. Chi-squared tests, Fisher exact tests, and Mann Whitney U tests were used to summarize the radiologic manifestations of patients and controls.

Results: We assessed 163 SSc patients and 231 controls. Widening of the periodontal ligament space (PLS) (P < .001), with higher percentage of teeth with PLS widening (P < .001), was significantly more frequent in patients with SSc than in controls. The most significant differences between the two groups were found in the molars and premolars (P < .001). Moreover, 26% of the patients with SSc had a periapical PLS greater than 0.19 mm compared with 13% of the controls (P = .003). Patients with SSc had significantly more erosions compared with controls (14.5% vs. 3.6%; P < .001), mostly in the condyles (P = .022), coronoid processes (P = .005) and other locations (P = .012).

Conclusion: Patients with SSc had more teeth with PLS widening and erosions of the mandible compared with controls.

Citing Articles

Current Perspectives on Periodontitis in Systemic Sclerosis: Associative Relationships, Pathogenic Links, and Best Practices.

Ciurea A, Rednic N, Soanca A, Micu I, Stanomir A, Onet D Diagnostics (Basel). 2023; 13(5).

PMID: 36899985 PMC: 10000920. DOI: 10.3390/diagnostics13050841.

Systemic sclerosis gastrointestinal dysmotility: risk factors, pathophysiology, diagnosis and management.

McMahan Z, Kulkarni S, Chen J, Chen J, Xavier R, Pasricha P Nat Rev Rheumatol. 2023; 19(3):166-181.

PMID: 36747090 DOI: 10.1038/s41584-022-00900-6.

Orofacial consequences of systemic sclerosis: A systematic review.

Smirani R, Poursac N, Naveau A, Schaeverbeke T, Devillard R, Truchetet M J Scleroderma Relat Disord. 2022; 3(1):81-90.

PMID: 35382129 PMC: 8892883. DOI: 10.1177/2397198317746966.

Dental implants in patients suffering from systemic sclerosis: a retrospective analysis of clinical outcomes in a case series with 24 patients.

Jackowski J, Strietzel F, Hunzelmann N, Parwani P, Jackowski A, Benz K Int J Implant Dent. 2021; 7(1):118.

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Dysphagia, reflux and related sequelae due to altered physiology in scleroderma.

Kadakuntla A, Juneja A, Sattler S, Agarwal A, Panse D, Zakhary N World J Gastroenterol. 2021; 27(31):5201-5218.

PMID: 34497445 PMC: 8384755. DOI: 10.3748/wjg.v27.i31.5201.

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