Renal Replacement Therapy in Acute Kidney Injury: Controversy and Consensus

Overview

Journal Crit Care

Specialty Critical Care

Date 2015 Apr 19

PMID 25887923

Citations 57

Authors

Claudio Ronco

Zaccaria Ricci

Daniel De Backer

John A Kellum

Fabio S Taccone

Michael Joannidis

Peter Pickkers

Vincenzo Cantaluppi

Franco Turani

Patrick Saudan

Rinaldo Bellomo

Olivier Joannes-Boyau

Massimo Antonelli

Didier Payen

John R Prowle

Jean-Louis Vincent

Affiliations

Soon will be listed here.

Abstract

Renal replacement therapies (RRTs) represent a cornerstone in the management of severe acute kidney injury. This area of intensive care and nephrology has undergone significant improvement and evolution in recent years. Continuous RRTs have been a major focus of new technological and treatment strategies. RRT is being used increasingly in the intensive care unit, not only for renal indications but also for other organ-supportive strategies. Several aspects related to RRT are now well established, but others remain controversial. In this review, we review the available RRT modalities, covering technical and clinical aspects. We discuss several controversial issues, provide some practical recommendations, and where possible suggest a research agenda for the future.

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References

Davenport A, Will E, Davison A . Early changes in intracranial pressure during haemofiltration treatment in patients with grade 4 hepatic encephalopathy and acute oliguric renal failure. Nephrol Dial Transplant. 1990; 5(3):192-8. DOI: 10.1093/ndt/5.3.192. View

Patarroyo M, Wehbe E, Hanna M, Taylor D, Starling R, Demirjian S . Cardiorenal outcomes after slow continuous ultrafiltration therapy in refractory patients with advanced decompensated heart failure. J Am Coll Cardiol. 2012; 60(19):1906-12. DOI: 10.1016/j.jacc.2012.08.957. View

Lindhoff-Last E, Betz C, Bauersachs R . Use of a low-molecular-weight heparinoid (danaparoid sodium) for continuous renal replacement therapy in intensive care patients. Clin Appl Thromb Hemost. 2001; 7(4):300-4. DOI: 10.1177/107602960100700409. View

Payen D, de Pont A, Sakr Y, Spies C, Reinhart K, Vincent J . A positive fluid balance is associated with a worse outcome in patients with acute renal failure. Crit Care. 2008; 12(3):R74. PMC: 2481469. DOI: 10.1186/cc6916. View

Cantaluppi V, Assenzio B, Pasero D, Romanazzi G, Pacitti A, Lanfranco G . Polymyxin-B hemoperfusion inactivates circulating proapoptotic factors. Intensive Care Med. 2008; 34(9):1638-45. PMC: 2517091. DOI: 10.1007/s00134-008-1124-6. View

Wu V, Wang C, Wang W, Lin Y, Hu F, Chen Y . Sustained low-efficiency dialysis versus continuous veno-venous hemofiltration for postsurgical acute renal failure. Am J Surg. 2009; 199(4):466-76. DOI: 10.1016/j.amjsurg.2009.01.007. View

Joannes-Boyau O, Honore P, Perez P, Bagshaw S, Grand H, Canivet J . High-volume versus standard-volume haemofiltration for septic shock patients with acute kidney injury (IVOIRE study): a multicentre randomized controlled trial. Intensive Care Med. 2013; 39(9):1535-46. DOI: 10.1007/s00134-013-2967-z. View

Atan R, Crosbie D, Bellomo R . Techniques of extracorporeal cytokine removal: a systematic review of human studies. Ren Fail. 2013; 35(8):1061-70. DOI: 10.3109/0886022X.2013.815089. View

de Geus H, Betjes M, Bakker J . Neutrophil gelatinase-associated lipocalin clearance during veno-venous continuous renal replacement therapy in critically ill patients. Intensive Care Med. 2010; 36(12):2156-7. PMC: 2981741. DOI: 10.1007/s00134-010-2015-1. View

10.

Murugan R, Wen X, Shah N, Lee M, Kong L, Pike F . Plasma inflammatory and apoptosis markers are associated with dialysis dependence and death among critically ill patients receiving renal replacement therapy. Nephrol Dial Transplant. 2014; 29(10):1854-64. PMC: 4173817. DOI: 10.1093/ndt/gfu051. View

11.

Mishra J, Dent C, Tarabishi R, Mitsnefes M, Ma Q, Kelly C . Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet. 2005; 365(9466):1231-8. DOI: 10.1016/S0140-6736(05)74811-X. View

12.

Schneider A, Bellomo R, Bagshaw S, Glassford N, Lo S, Jun M . Choice of renal replacement therapy modality and dialysis dependence after acute kidney injury: a systematic review and meta-analysis. Intensive Care Med. 2013; 39(6):987-97. DOI: 10.1007/s00134-013-2864-5. View

13.

Ronco C, Brendolan A, Lonnemann G, Bellomo R, Piccinni P, Digito A . A pilot study of coupled plasma filtration with adsorption in septic shock. Crit Care Med. 2002; 30(6):1250-5. DOI: 10.1097/00003246-200206000-00015. View

14.

Ricci Z, Salvatori G, Bonello M, Ratanarat R, Andrikos E, Dan M . A new machine for continuous renal replacement therapy: from development to clinical testing. Expert Rev Med Devices. 2005; 2(1):47-55. DOI: 10.1586/17434440.2.1.47. View

15.

Parienti J, Thirion M, Megarbane B, Souweine B, Ouchikhe A, Polito A . Femoral vs jugular venous catheterization and risk of nosocomial events in adults requiring acute renal replacement therapy: a randomized controlled trial. JAMA. 2008; 299(20):2413-22. DOI: 10.1001/jama.299.20.2413. View

16.

Bournazos S, Rennie J, Hart S, Dransfield I . Choice of anticoagulant critically affects measurement of circulating platelet-leukocyte complexes. Arterioscler Thromb Vasc Biol. 2007; 28(1):e2-3. DOI: 10.1161/ATVBAHA.107.153387. View

17.

Wu V, Ko W, Chang H, Chen Y, Lin Y, Shiao C . Risk factors of early redialysis after weaning from postoperative acute renal replacement therapy. Intensive Care Med. 2007; 34(1):101-8. DOI: 10.1007/s00134-007-0813-x. View

18.

Hoste E, Maitland K, Brudney C, Mehta R, Vincent J, Yates D . Four phases of intravenous fluid therapy: a conceptual model. Br J Anaesth. 2014; 113(5):740-7. PMC: 6863743. DOI: 10.1093/bja/aeu300. View

19.

Kiser T, Fish D . Evaluation of bivalirudin treatment for heparin-induced thrombocytopenia in critically ill patients with hepatic and/or renal dysfunction. Pharmacotherapy. 2006; 26(4):452-60. DOI: 10.1592/phco.26.4.452. View

20.

Cruz D, Antonelli M, Fumagalli R, Foltran F, Brienza N, Donati A . Early use of polymyxin B hemoperfusion in abdominal septic shock: the EUPHAS randomized controlled trial. JAMA. 2009; 301(23):2445-52. DOI: 10.1001/jama.2009.856. View