Regioselective C-H Bond Amination by Aminoiodanes

Overview

Journal Chem Commun (Camb)

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2015 Jan 31

PMID 25632832

Citations 1

Authors

Abhishek A Kantak

Louis Marchetti

Brenton DeBoef

Affiliations

Soon will be listed here.

Abstract

A new approach for the direct amination of 2-phenylpyridine derivatives using a diphthalimide-iodane and copper triflate has been developed. A series of different 2-phenylpyridine derivatives were aminated with yields up to 88%. Mechanistic investigations indicate that the reaction proceeds via a copper-mediated single electron transfer.

Citing Articles

A comprehensive overview of directing groups applied in metal-catalysed C-H functionalisation chemistry.

Sambiagio C, Schonbauer D, Blieck R, Dao-Huy T, Pototschnig G, Schaaf P Chem Soc Rev. 2018; 47(17):6603-6743.

PMID: 30033454 PMC: 6113863. DOI: 10.1039/c8cs00201k.

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