Impact of Vitamin D Supplementation on Adiposity in African-Americans

Overview

Journal Nutr Diabetes

Specialties Endocrinology
Nutritional Sciences

Date 2015 Jan 20

PMID 25599559

Citations 2

Authors

P D Chandler

J B Scott

B F Drake

K Ng

A T Chan

B W Hollis

K M Emmons

E L Giovannucci

C S Fuchs

G G Bennett

Affiliations

Soon will be listed here.

Abstract

Background: African-Americans have higher rates of obesity-associated chronic diseases. Serum 25-hydroxyvitamin D (25(OH)D) shows an inverse association with obesity status. We investigated whether vitamin D supplementation changes body mass index (BMI).

Subjects: In total, 328 overweight African-Americans were enrolled over three consecutive winter periods (2007-2010) into a randomized, double-blind, placebo-controlled trial to receive cholecalciferol supplementation (0, 1000 international units (IU), 2000 IU or 4000 IU per day) for 3 months. Plasma concentrations of 25(OH)D and anthropometric measurements were done at baseline, 3 and 6 months.

Results: At 3 months, vitamin D supplementation in three dose groups (1000 IU, 2000 IU or 4000 IU per day) did not cause any significant changes in BMI as compared with placebo group 3-month change in BMI per 1000 IU per day estimate (SE): 0.01 (0.039); P=0.78.

Conclusions: In overweight African-Americans, short-term high-dose vitamin D supplementation did not alter BMI.

Citing Articles

Seasonal variation of total and bioavailable 25-hydroxyvitamin D [25(OH)D] in the healthy adult Slovenian population.

Osredkar J, Vicic V, Hribar M, Benedik E, Siuka D, Jerin A Acta Biochim Pol. 2024; 71:13108.

PMID: 39323456 PMC: 11422067. DOI: 10.3389/abp.2024.13108.

Nutritional supplements improve cardiovascular risk factors in overweight and obese patients: A Bayesian network meta-analysis.

Yu Z, Zhao D, Liu X Front Nutr. 2023; 10:1140019.

PMID: 37063314 PMC: 10098366. DOI: 10.3389/fnut.2023.1140019.

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