The Major Kidney Band 3 Gene Transcript Predicts an Amino-terminal Truncated Band 3 Polypeptide

Overview

Journal J Biol Chem

Specialty Biochemistry

Date 1989 May 15

PMID 2542243

Citations 49

Authors

F C Brosius 3rd

S L Alper

A M Garcia

H F Lodish

Affiliations

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Abstract

We have characterized multiple transcripts from the band 3 gene expressed in rat and mouse kidney. In each species, the major transcript lacks sequence from the first three exons of the band 3 gene. The murine transcript predicts a kidney band 3 polypeptide with a truncated amino terminus, lacking the first 79 amino acids of erythroid band 3. When expressed in Xenopus oocytes this truncated band 3 functions in anion transport.

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