Preterm Birth and Its Long-term Effects: Methylation to Mechanisms

Overview

Journal Biology (Basel)

Publisher MDPI

Specialty Biology

Date 2014 Sep 27

PMID 25256426

Citations 31

Authors

Sasha E Parets

Carrie E Bedient

Ramkumar Menon

Alicia K Smith

Affiliations

Soon will be listed here.

Abstract

The epigenetic patterns established during development may influence gene expression over a lifetime and increase susceptibility to chronic disease. Being born preterm (<37 weeks of gestation) is associated with increased risk mortality and morbidity from birth until adulthood. This brief review explores the potential role of DNA methylation in preterm birth (PTB) and its possible long-term consequences and provides an overview of the physiological processes central to PTB and recent DNA methylation studies of PTB.

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