Four New Polycyclic Meroterpenoids from Ganoderma Cochlear

Overview

Journal Org Lett

Publisher American Chemical Society

Specialties Biochemistry
Chemistry

Date 2014 Sep 6

PMID 25192355

Citations 12

Authors

Xing-Rong Peng

Jie-Qing Liu

Luo-Sheng Wan

Xiao-Nian Li

Yu-Xin Yan

Ming-Hua Qiu

Affiliations

Soon will be listed here.

Abstract

Four pairs of new polycyclic-meroterpenoid enantiomers, ganocins A-C (1-3) possessing a spiro[4,5]decane ring system, along with ganocin D (4) with an eight-membered ring, were isolated from the fruiting bodies of Ganoderma cochlear. Their structures were determined by spectroscopic data and X-ray diffraction crystallography. Their anti-AChE activities were evaluated, and a possible biogenetic pathway was also proposed.

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