Vitamin D Deficiency and Altered Bone Mineral Metabolism in HIV-infected Individuals

Overview

Journal Curr HIV/AIDS Rep

Publisher Current Science

Specialty Infectious Diseases

Date 2014 Jun 26

PMID 24962286

Citations 8

Authors

Allison Ross Eckard

Grace A McComsey

Affiliations

Soon will be listed here.

Abstract

Although patients with HIV infection are living decades longer than before with the advent of combination antiretroviral therapy, they have an increased rate of co-morbidities associated with chronic HIV, such as osteoporosis, cardiovascular disease, and immune dysfunction. Many of these complications are known to be affected by vitamin D status in the general population. Thus, the high rate of vitamin D deficiency among HIV-infected patients is alarming. Many observational and cohort studies have demonstrated that vitamin D deficiency is associated with these HIV-related complications, but randomized, placebo-controlled trials are limited. This paper reviews recent data on vitamin D deficiency in HIV infection.

Citing Articles

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Secondary Osteoporosis and Metabolic Bone Diseases.

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Endocrinological aspects of HIV infection.

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Bone mineral density in people living with HIV: a narrative review of the literature.

Kruger M, Nell T AIDS Res Ther. 2017; 14(1):35.

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Vitamin D receptor deficit induces activation of renin angiotensin system via SIRT1 modulation in podocytes.

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