Cryptosporidium Parvum IId Family: Clonal Population and Dispersal from Western Asia to Other Geographical Regions

Overview

Journal Sci Rep

Specialty Science

Date 2014 Feb 28

PMID 24572610

Citations 33

Authors

Rongjun Wang

Longxian Zhang

Charlotte Axen

Camilla Bjorkman

Fuchun Jian

Said Amer

Aiqin Liu

Yaoyu Feng

Guoquan Li

Chaochao Lv

Zifang Zhao

Meng Qi

Haiju Dong

Helei Wang

Yanru Sun

Changshen Ning

Lihua Xiao

Affiliations

Soon will be listed here.

Abstract

In this study, 111 Cryptosporidium parvum IId isolates from several species of animals in China, Sweden, and Egypt were subtyped by multilocus sequence typing (MLST). One to eleven subtypes were detected at each of the 12 microsatellite, minisatellite, and single nucleotide polymorphism (SNP) loci, forming 25 MLST subtypes. Host-adaptation and significant geographical segregation were both observed in the MLST subtypes. A clonal population structure was seen in C. parvum IId isolates from China and Sweden. Three ancestral lineages and the same RPGR sequence were shared by these isolates examined. Therefore, the present genetic observations including the higher nucleotide diversity of C. parvum IId GP60 sequences in Western Asia, as well as the unique distribution of IId subtypes (almost exclusively found in Asia, Europe, and Egypt) and in combination with the domestication history of cattle, sheep, and goats, indicated that C. parvum IId subtypes were probably dispersed from Western Asia to other geographical regions. More population genetic structure studies involving various C. parvum subtype families using high-resolution tools are needed to better elucidate the origin and dissemination of C. parvum in the world.

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References

Lv C, Zhang L, Wang R, Jian F, Zhang S, Ning C . Cryptosporidium spp. in wild, laboratory, and pet rodents in china: prevalence and molecular characterization. Appl Environ Microbiol. 2009; 75(24):7692-9. PMC: 2794099. DOI: 10.1128/AEM.01386-09. View

Imre K, Luca C, Costache M, Sala C, Morar A, Morariu S . Zoonotic Cryptosporidium parvum in Romanian newborn lambs (Ovis aries). Vet Parasitol. 2012; 191(1-2):119-22. DOI: 10.1016/j.vetpar.2012.08.020. View

Bandelt H, Forster P, Rohl A . Median-joining networks for inferring intraspecific phylogenies. Mol Biol Evol. 1999; 16(1):37-48. DOI: 10.1093/oxfordjournals.molbev.a026036. View

Ng J, Mackenzie B, Ryan U . Longitudinal multi-locus molecular characterisation of sporadic Australian human clinical cases of cryptosporidiosis from 2005 to 2008. Exp Parasitol. 2010; 125(4):348-56. DOI: 10.1016/j.exppara.2010.02.017. View

Beja-Pereira A, Caramelli D, Lalueza-Fox C, Vernesi C, Ferrand N, Casoli A . The origin of European cattle: evidence from modern and ancient DNA. Proc Natl Acad Sci U S A. 2006; 103(21):8113-8. PMC: 1472438. DOI: 10.1073/pnas.0509210103. View

Ajjampur S, Liakath F, Kannan A, Rajendran P, Sarkar R, Moses P . Multisite study of cryptosporidiosis in children with diarrhea in India. J Clin Microbiol. 2010; 48(6):2075-81. PMC: 2884513. DOI: 10.1128/JCM.02509-09. View

Plutzer J, Karanis P . Genotype and subtype analyses of Cryptosporidium isolates from cattle in Hungary. Vet Parasitol. 2007; 146(3-4):357-62. DOI: 10.1016/j.vetpar.2007.02.030. View

Widgren S, Frossling J . Spatio-temporal evaluation of cattle trade in Sweden: description of a grid network visualization technique. Geospat Health. 2010; 5(1):119-30. DOI: 10.4081/gh.2010.192. View

Wang L, Zhang H, Zhao X, Zhang L, Zhang G, Guo M . Zoonotic Cryptosporidium species and Enterocytozoon bieneusi genotypes in HIV-positive patients on antiretroviral therapy. J Clin Microbiol. 2012; 51(2):557-63. PMC: 3553929. DOI: 10.1128/JCM.02758-12. View

10.

Insulander M, Silverlas C, Lebbad M, Karlsson L, Mattsson J, Svenungsson B . Molecular epidemiology and clinical manifestations of human cryptosporidiosis in Sweden. Epidemiol Infect. 2012; 141(5):1009-20. PMC: 9151846. DOI: 10.1017/S0950268812001665. View

11.

Wang R, Wang H, Sun Y, Zhang L, Jian F, Qi M . Characteristics of Cryptosporidium transmission in preweaned dairy cattle in Henan, China. J Clin Microbiol. 2010; 49(3):1077-82. PMC: 3067708. DOI: 10.1128/JCM.02194-10. View

12.

De Waele V, Van den Broeck F, Huyse T, McGrath G, Higgins I, Speybroeck N . Panmictic structure of the Cryptosporidium parvum population in Irish calves: influence of prevalence and host movement. Appl Environ Microbiol. 2013; 79(8):2534-41. PMC: 3623186. DOI: 10.1128/AEM.03613-12. View

13.

Xiao L, Sulaiman I, Ryan U, Zhou L, Atwill E, Tischler M . Host adaptation and host-parasite co-evolution in Cryptosporidium: implications for taxonomy and public health. Int J Parasitol. 2002; 32(14):1773-85. DOI: 10.1016/s0020-7519(02)00197-2. View

14.

Xiao L . Molecular epidemiology of cryptosporidiosis: an update. Exp Parasitol. 2009; 124(1):80-9. DOI: 10.1016/j.exppara.2009.03.018. View

15.

Fernandez H, Hughes S, Vigne J, Helmer D, Hodgins G, Miquel C . Divergent mtDNA lineages of goats in an Early Neolithic site, far from the initial domestication areas. Proc Natl Acad Sci U S A. 2006; 103(42):15375-9. PMC: 1622831. DOI: 10.1073/pnas.0602753103. View

16.

Amer S, Zidan S, Feng Y, Adamu H, Li N, Xiao L . Identity and public health potential of Cryptosporidium spp. in water buffalo calves in Egypt. Vet Parasitol. 2012; 191(1-2):123-7. DOI: 10.1016/j.vetpar.2012.08.015. View

17.

Iqbal A, Lim Y, Surin J, Sim B . High diversity of Cryptosporidium subgenotypes identified in Malaysian HIV/AIDS individuals targeting gp60 gene. PLoS One. 2012; 7(2):e31139. PMC: 3275556. DOI: 10.1371/journal.pone.0031139. View

18.

Tanriverdi S, Widmer G . Differential evolution of repetitive sequences in Cryptosporidium parvum and Cryptosporidium hominis. Infect Genet Evol. 2006; 6(2):113-22. DOI: 10.1016/j.meegid.2005.02.002. View

19.

Mallon M, MacLeod A, Wastling J, Smith H, Reilly B, Tait A . Population structures and the role of genetic exchange in the zoonotic pathogen Cryptosporidium parvum. J Mol Evol. 2003; 56(4):407-17. DOI: 10.1007/s00239-002-2412-3. View

20.

Feng X, Rich S, Tzipori S, Widmer G . Experimental evidence for genetic recombination in the opportunistic pathogen Cryptosporidium parvum. Mol Biochem Parasitol. 2002; 119(1):55-62. DOI: 10.1016/s0166-6851(01)00393-0. View