Identification of a Neutralizing Epitope Shared by Bluetongue Virus Serotypes 2 and 13

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 1988 Jul 1

PMID 2453681

Citations 1

Authors

S Ristow

L Leendersten

J Gorham

T Yilma

Affiliations

Soon will be listed here.

Abstract

The serotypes of bluetongue virus (BTV) are classified by differences in neutralization commonly induced by P2, a major surface protein. A BTV serotype 13 (BTV-13) monoclonal antibody, 4B13-207A, immunoprecipitated P2s of BTV-13 and BTV-2 and also neutralized both viruses. These data indicate that P2s from BTV-13 and BTV-2 share a common neutralizing epitope that is not detected by neutralizing polyclonal antibody to BTV-13.

Citing Articles

Serological Cross-Reactions between Expressed VP2 Proteins from Different Bluetongue Virus Serotypes.

Fay P, Mohd Jaafar F, Batten C, Attoui H, Saunders K, Lomonossoff G Viruses. 2021; 13(8).

PMID: 34452321 PMC: 8402635. DOI: 10.3390/v13081455.

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