Genome Segment Reassortment Between Two Serotypes of Bluetongue Virus in a Natural Host

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 1987 Sep 1

PMID 3039160

Citations 18

Authors

J L Stott

R D Oberst

M B Channell

B I Osburn

Affiliations

Soon will be listed here.

Abstract

The occurrence of genome segment reassortment between two antigenically related orbiviruses was demonstrated in cattle. Individual virus clones were isolated by cell culture plaque assays directly from the blood of a calf infected with two serotypes of bluetongue virus. The majority (89%) of progeny viruses isolated from the calf represented reassortant viruses. A minimum of six genome segments participated in reassortment, with 16 unique reassortant constellations being identified. Such genome segment reassortment between unique, though antigenically related, orbiviruses has undoubtedly played a major role in generating the extensive phenotypic and genotypic diversity that is characteristic of this serogroup.

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