Evidence for Maternal Imprinting of 45S Ribosomal RNA Genes in Xenopus Hybrids

Overview

Journal Dev Genes Evol

Specialty Biology

Date 2014 Jan 31

PMID 24477594

Citations 3

Authors

Pawel Michalak

Affiliations

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Abstract

We discovered that gene clusters of 45S ribosomal RNA in Xenopus hybrid frogs are maternally imprinted, similar to X chromosome inactivation in marsupial females. Paternal expression was partly restored after chemical inhibition of histone deacetylation during larval stages. This provides a new spectacular example of epigenetic silencing and first evidence of genomic imprinting in amphibians.

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