Characterizing 5-methylcytosine in the Mammalian Epitranscriptome

Overview

Journal Genome Biol

Specialties Biology
Genetics

Date 2013 Nov 30

PMID 24286375

Citations 118

Authors

Shobbir Hussain

Jelena Aleksic

Sandra Blanco

Sabine Dietmann

Michaela Frye

Affiliations

Soon will be listed here.

Abstract

The post-transcriptional modification 5-methylcytosine (m5C) occurs in a wide range of coding and non-coding RNAs. We describe transcriptome-wide approaches to capture the global m5C RNA methylome. We also discuss the potential functions of m5C in RNA and compare them to 6-methyladenosine modifications.

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