Who is at Risk of Long Hospital Stay Among Patients Admitted to Geriatric Acute Care Unit? Results from a Prospective Cohort Study
Overview
Nutritional Sciences
Affiliations
Objective: (1) To confirm that vitamin D deficiency, defined as serum 25-hydroxyvitamin D (25OHD) concentration < 25 nmol/L, was associated with long length-of-stay (LOS) among older inpatients admitted to geriatric acute care unit; and (2) to examine which combination of risk factors of longer LOS including vitamin D deficiency best predicted longer LOS.
Study Design And Setting: Based on a prospective cohort study with a 25-day follow-up on average, 531 consecutive older inpatients (mean age 85.0±7.2 years, 59.1% women) admitted to the geriatric acute care unit of Angers University Hospital, France, were included.
Results: Linear regression models showed that male gender (P<0.025), delirium (P<0.015) and vitamin D deficiency (P<0.001) were independently associated with a longer LOS. The highest risk of a longer LOS was shown while combining vitamin D deficiency with male gender (Odds ratio (OR)=3.70 with P< 0.001). The risk increased significantly while delirium was associated with these two baseline characteristics (OR=4.76 with P=0.001). Kaplan-Meier distributions of discharge differed significantly between participants who had or not the combination of the 3 criteria (P<0.007).
Conclusions: Vitamin D deficiency, delirium and male gender were significant risk factors for a longer LOS in the studied sample of older inpatients.
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Association between vitamin D concentration and delirium in hospitalized patients: A meta-analysis.
Fu N, Miao M, Li N, Zeng S, Zhu R, Zhang J PLoS One. 2023; 18(2):e0281313.
PMID: 36753475 PMC: 9907811. DOI: 10.1371/journal.pone.0281313.
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Beirne A, McCarroll K, Walsh J, Casey M, Laird E, McNulty H Nutrients. 2021; 13(2).
PMID: 33672800 PMC: 7918803. DOI: 10.3390/nu13020616.
Non-pharmacological approaches in the prevention of delirium.
Salvi F, Young J, Lucarelli M, Aquilano A, Luzi R, DellAquila G Eur Geriatr Med. 2020; 11(1):71-81.
PMID: 32297241 DOI: 10.1007/s41999-019-00260-7.