Exposure to Ambient Air Particulate Matter and Non-alcoholic Fatty Liver Disease

Overview

Journal World J Gastroenterol

Publisher Baishideng Publishing Group

Specialty Gastroenterology

Date 2013 Jul 11

PMID 23840139

Citations 23

Authors

Giovanni Tarantino

Domenico Capone

Carmine Finelli

Affiliations

Soon will be listed here.

Abstract

The present study was designed to alert the public opinion and policy makers on the supposed enhancing effects of exposure to ambient air particulate matter with aerodynamic diameters < 2.5 mm (PM2.5) on non-alcoholic fatty liver disease (NAFLD), the most common chronic liver disease in Western countries. For far too long literature data have been fixated on pulmonary diseases and/or cardiovascular disease, as consequence of particulate exposure, ignoring the link between the explosion of obesity with related syndromes such as NAFLD and air pollution, the worst characteristics of nowadays civilization. In order to delineate a clear picture of this major health problem, further studies should investigate whether and at what extent cigarette smoking and exposure to ambient air PM2.5 impact the natural history of patients with obesity-related NAFLD, i.e., development of non alcoholic steatohepatitis, disease characterized by a worse prognosis due its progression towards fibrosis and hepatocarcinoma.

Citing Articles

Medaka liver developed Human NAFLD-NASH transcriptional signatures in response to ancestral bisphenol A exposure.

Chakraborty S, Anand S, Bhandari R Res Sq. 2024; .

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Sex-specific expression of the human NAFLD-NASH transcriptional signatures in the liver of medaka with a history of ancestral bisphenol A exposure.

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Associations of long-term exposure to air pollution and physical activity with the risk of systemic inflammation-induced multimorbidity in Chinese adults: results from the China multi-ethnic cohort study (CMEC).

Li Y, Guo B, Meng Q, Yin L, Chen L, Wang X BMC Public Health. 2023; 23(1):2556.

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Serum metabolome and liver transcriptome reveal acrolein inhalation-induced sex-specific homeostatic dysfunction.

Alewel D, Rentschler K, Jackson T, Schladweiler M, Astriab-Fisher A, Evansky P Sci Rep. 2023; 13(1):21179.

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High glucose enhances the activation of NLRP3 inflammasome by ambient fine particulate matter in alveolar macrophages.

Mo Y, Mo L, Zhang Y, Zhang Y, Yuan J, Zhang Q Part Fibre Toxicol. 2023; 20(1):41.

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