An Efficient Synthesis of Aldohexose-derived Piperidine Nitrones: Precursors of Piperidine Iminosugars

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2013 May 24

PMID 23698053

Authors

Hui Zhao

Wen-Bo Zhao

Jian-She Zhu

Yue-Mei Jia

Chu-Yi Yu

Affiliations

Soon will be listed here.

Abstract

D-glucopyranose-derived and L-idopyranose-derived piperidine nitrones were synthesized in good overall yields through six-step reaction sequence starting from readily available 2,3,4,6-tetra-O-benzyl-D-glucopyranose. The method is efficient and could be general for the synthesis of aldohexose-derived piperidine nitrones which are precursors of piperidine iminosugars.

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