» Articles » PMID: 23456749

Magnetic Resonance Imaging in the Prenatal Diagnosis of Neural Tube Defects

Overview
Publisher Springer
Specialty Radiology
Date 2013 Mar 5
PMID 23456749
Citations 9
Authors
Affiliations
Soon will be listed here.
Abstract

Objective: To assess the role of magnetic resonance imaging (MRI) in the prenatal diagnosis of neural tube defects (NTDs).

Background: NTDs comprise a heterogeneous group of congenital anomalies that derive from the failure of the neural tube to close. Advances in ultrasonography and MRI have considerably improved the diagnosis and treatment of NTDs both before and after birth. Ultrasonography is the first technique in the morphological study of the fetus, and it often makes it possible to detect or suspect NTDs. Fetal MRI is a complementary technique that makes it possible to clear up uncertain ultrasonographic findings and to detect associated anomalies that might go undetected at ultrasonography. The progressive incorporation of intrauterine treatments makes an accurate diagnosis of NTDs essential to ensure optimal perinatal management. The ability of fetal MRI to detect complex anomalies that affect different organs has been widely reported, and it can be undertaken whenever NTDs are suspected.

Conclusion: We describe the normal appearance of fetal neural tube on MRI, and we discuss the most common anomalies involving the structures and the role of fetal MRI in their assessment.

Key Points: • To learn about the normal anatomy of the neural tube on MRI • To recognise the MR appearance of neural tube defects • To understand the value of MRI in assessing NTDs.

Citing Articles

Diagnostic Utility of 3D Gradient-Echo MR Imaging Sequences through the Filum Compared with Spin-Echo T1 in Children with Concern for Tethered Cord.

Rafiee F, Mehan W, Rincon S, Rohatgi S, Rapalino O, Buch K AJNR Am J Neuroradiol. 2023; 44(3):323-327.

PMID: 36797030 PMC: 10187807. DOI: 10.3174/ajnr.A7791.


Torcular pseudomass is frequently detected on fetal magnetic resonance imaging and reduces with gestational age.

Miranda A, Bem P, Araujo A, Brito C, Nunes J, Geraldo A Pediatr Radiol. 2022; 53(3):470-478.

PMID: 36437371 DOI: 10.1007/s00247-022-05549-7.


An automatic multi-tissue human fetal brain segmentation benchmark using the Fetal Tissue Annotation Dataset.

Payette K, De Dumast P, Kebiri H, Ezhov I, Paetzold J, Shit S Sci Data. 2021; 8(1):167.

PMID: 34230489 PMC: 8260784. DOI: 10.1038/s41597-021-00946-3.


Perspectives on urological care in spina bifida patients.

Moussa M, Papatsoris A, Chakra M, Fares Y, Dabboucy B, Dellis A Intractable Rare Dis Res. 2021; 10(1):1-10.

PMID: 33614369 PMC: 7882087. DOI: 10.5582/irdr.2020.03077.


Prenatal counseling: Guidelines for the care of people with spina bifida.

Church P, Castillo H, Castillo J, Berndl A, Brei T, Heuer G J Pediatr Rehabil Med. 2020; 13(4):461-466.

PMID: 33285644 PMC: 7838969. DOI: 10.3233/PRM-200735.


References
1.
Scott Adzick N . Fetal surgery for myelomeningocele: trials and tribulations. Isabella Forshall Lecture. J Pediatr Surg. 2012; 47(2):273-81. PMC: 3278714. DOI: 10.1016/j.jpedsurg.2011.11.021. View

2.
McLone D, Dias M . The Chiari II malformation: cause and impact. Childs Nerv Syst. 2003; 19(7-8):540-50. DOI: 10.1007/s00381-003-0792-3. View

3.
Kirke P, Molloy A, Daly L, Burke H, Weir D, Scott J . Maternal plasma folate and vitamin B12 are independent risk factors for neural tube defects. Q J Med. 1993; 86(11):703-8. View

4.
Duczkowska A, Bekiesinska-Figatowska M, Herman-Sucharska I, Duczkowski M, Romaniuk-Doroszewska A, Jurkiewicz E . Magnetic resonance imaging in the evaluation of the fetal spinal canal contents. Brain Dev. 2010; 33(1):10-20. DOI: 10.1016/j.braindev.2010.01.003. View

5.
Griffiths P, Widjaja E, Paley M, Whitby E . Imaging the fetal spine using in utero MR: diagnostic accuracy and impact on management. Pediatr Radiol. 2006; 36(9):927-33. DOI: 10.1007/s00247-006-0234-y. View