Do Patients with Osteoporosis Have an Increased Prevalence of Periodontal Disease? A Cross-sectional Study

Overview

Journal Osteoporos Int

Specialties Endocrinology
Orthopedics

Date 2013 Jan 24

PMID 23340948

Citations 15

Authors

E J Marjanovic

H N Southern

P Coates

J E Adams

T Walsh

K Horner

H Devlin

Affiliations

Soon will be listed here.

Abstract

Unlabelled: The study examined if women with osteoporosis were at increased risk of periodontal disease. Three hundred eighty females aged 45-65 years with recent dual-energy X-ray absorptiometry (DXA) scans of the spine and proximal femur agreed to a dental examination. No association was established between the presence of severe periodontal disease and osteoporosis.

Introduction: The purpose of this study is to determine whether patients with osteoporosis have an increased severity and extent of periodontal disease, taking full account of confounding factors.

Methods: Volunteer dentate women (45-65 years), who had undergone recent DXA of the femur and lumbar spine, received a clinical examination of their periodontal tissues by a single trained operator who was blind to the subject's osteoporosis status. Clinical examinations were performed within 6 months of the DXA. Basic Periodontal Examination score, gingival bleeding score, periodontal pocket depth, recession and calculus were the periodontal outcome measures. Potential confounding factors were recorded. Logistic regression was performed for the dichotomous outcome measure of severe periodontal disease (present or absent) with osteoporotic status, adjusting for confounding factors.

Results: There were 380 dentate participants for whom DXA data were available. Of these, 98 had osteoporosis. When compared with osteoporotic subjects, those with normal bone mineral density were significantly younger (p = 0.01), had a higher body mass index (p = 0.03) and had more teeth (p = 0.01). The prevalence of severe periodontal disease in the sample was 39 %. The unadjusted odds ratio for the association between osteoporosis and severe periodontal disease was 1.21 (0.76 to 1.93). The adjusted odds ratio analysis including other covariates (age, smoking, hormone replacement therapy, alcohol) was 0.99 (0.61 to 1.61).

Conclusion: No association was established between the presence of severe periodontal disease and osteoporosis.

Citing Articles

Association between periodontal disease and osteoporosis in postmenopausal women: A systematic review and meta-analysis.

Qi J, Chen J, Pang Y, Guo Y, Chen G, Liu Y Heliyon. 2023; 9(11):e20922.

PMID: 37920517 PMC: 10618781. DOI: 10.1016/j.heliyon.2023.e20922.

Periodontal Health and Disease in the Context of Systemic Diseases.

Isola G, Santonocito S, Lupi S, Polizzi A, Sclafani R, Patini R Mediators Inflamm. 2023; 2023:9720947.

PMID: 37214190 PMC: 10199803. DOI: 10.1155/2023/9720947.

Association between periodontitis and osteoporosis in United States adults from the National Health and Nutrition Examination Survey: a cross-sectional analysis.

Peng J, Chen J, Liu Y, Lyu J, Zhang B BMC Oral Health. 2023; 23(1):254.

PMID: 37131215 PMC: 10155350. DOI: 10.1186/s12903-023-02990-4.

Overview on postmenopausal osteoporosis and periodontitis: The therapeutic potential of phytoestrogens against alveolar bone loss.

Jayusman P, Nasruddin N, Baharin B, Ibrahim N, Hairi H, Shuid A Front Pharmacol. 2023; 14:1120457.

PMID: 36909165 PMC: 9995413. DOI: 10.3389/fphar.2023.1120457.

The relationship between FOSB and SOCS3 gene polymorphisms and the susceptibility to periodontitis and osteopenia in the Chinese population.

Liu L, Zhang L, Li Y, Wang Y, He L, Song L Odontology. 2022; 110(4):747-758.

PMID: 35661052 DOI: 10.1007/s10266-022-00718-4.

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