Global Phylogeny of Shigella Sonnei Strains from Limited Single Nucleotide Polymorphisms (SNPs) and Development of a Rapid and Cost-effective SNP-typing Scheme for Strain Identification by High-resolution Melting Analysis
Overview
Authors
Affiliations
The current Shigella sonnei pandemic involves geographically associated, multidrug-resistant clones. This study has demonstrated that S. sonnei phylogeny can be accurately defined with limited single nucleotide polymorphisms (SNPs). By typing 6 informative SNPs using a high-resolution melting (HRM) assay, major S. sonnei lineages/sublineages can be identified as defined by whole-genome variation.
Abelman R, Mikanatha N, Figler H, Dudley E Microb Genom. 2019; 5(5).
PMID: 31099740 PMC: 6562246. DOI: 10.1099/mgen.0.000270.
Comparative Genomic and Phylogenetic Analysis of a Shiga Toxin Producing (STSS) Strain.
Svab D, Balint B, Vasarhelyi B, Maroti G, Toth I Front Cell Infect Microbiol. 2017; 7:229.
PMID: 28611956 PMC: 5447701. DOI: 10.3389/fcimb.2017.00229.
Aanensen D, Feil E, Holden M, Dordel J, Yeats C, Fedosejev A mBio. 2016; 7(3).
PMID: 27150362 PMC: 4959656. DOI: 10.1128/mBio.00444-16.
Genome diversity of Shigella boydii.
Kania D, Hazen T, Hossain A, Nataro J, Rasko D Pathog Dis. 2016; 74(4):ftw027.
PMID: 27056949 PMC: 5985476. DOI: 10.1093/femspd/ftw027.
Salmonella, Shigella, and yersinia.
Dekker J, Frank K Clin Lab Med. 2015; 35(2):225-46.
PMID: 26004640 PMC: 4443274. DOI: 10.1016/j.cll.2015.02.002.