Molecular Logic Gates for DNA Analysis: Detection of Rifampin Resistance in M. Tuberculosis DNA

Overview

Journal Angew Chem Int Ed Engl

Specialty Chemistry

Date 2012 Aug 14

PMID 22888076

Citations 8

Authors

Evan M Cornett

Eleanor A Campbell

George Gulenay

Evan Peterson

Neha Bhaskar

Dmitry M Kolpashchikov

Affiliations

Soon will be listed here.

Abstract

Elementary, Dr. Watson! A combination of YES and OR logic gates was applied to differentiate between DNA sequences of wild-type and rifampin-resistant (Rif(r)) Mycobacterium tuberculosis (Mtb) in a multiplex real-time fluorescent assay.

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Alphanumerical Visual Display Made of DNA Logic Gates for Drug Susceptibility Testing of Pathogens.

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