Evan M Cornett
Overview
Explore the profile of Evan M Cornett including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
26
Citations
516
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Berryhill C, Evans T, Doud E, Smith-Kinnaman W, Hanquier J, Mosley A, et al.
J Proteome Res
. 2025 Jan;
24(2):550-561.
PMID: 39778878
Growing evidence shows that lysine methylation is a widespread protein post-translational modification (PTM) that regulates protein function on histone and nonhistone proteins. Numerous studies have demonstrated that the dysregulation of...
2.
Berryhill C, Evans T, Doud E, Smith-Kinnaman W, Hanquier J, Mosley A, et al.
bioRxiv
. 2024 Sep;
PMID: 39345446
Growing evidence shows that lysine methylation is a widespread protein post-translational modification that regulates protein function on histone and non-histone proteins. Numerous studies have demonstrated that dysregulation of lysine methylation...
3.
Berryhill C, Doud E, Hanquier J, Smith-Kinnaman W, McCourry D, Mosley A, et al.
Biomolecules
. 2024 Jul;
14(7).
PMID: 39062531
DZNep (3-deazaneplanocin A) is commonly used to reduce lysine methylation. DZNep inhibits S-adenosyl-l-homocysteine hydrolase (AHCY), preventing the conversion of S-adenosyl-l-homocysteine (SAH) into L-homocysteine. As a result, the SAM-to-SAH ratio decreases,...
4.
Chomiak A, Tiedemann R, Liu Y, Kong X, Cui Y, Wiseman A, et al.
Sci Adv
. 2024 Mar;
10(13):eadk4423.
PMID: 38536911
DNA methyltransferase inhibitor (DNMTi) efficacy in solid tumors is limited. Colon cancer cells exposed to DNMTi accumulate lysine-27 trimethylation on histone H3 (H3K27me3). We propose this Enhancer of Zeste Homolog...
5.
Hanquier J, Sanders K, Berryhill C, Sahoo F, Hudmon A, Vilseck J, et al.
J Biol Chem
. 2023 Mar;
299(5):104651.
PMID: 36972790
Lysine methylation is a dynamic, posttranslational mark that regulates the function of histone and nonhistone proteins. Many of the enzymes that mediate lysine methylation, known as lysine methyltransferases (KMTs), were...
6.
Berryhill C, Hanquier J, Doud E, Cordeiro-Spinetti E, Dickson B, Rothbart S, et al.
Sci Rep
. 2023 Jan;
13(1):377.
PMID: 36611042
Lysine methylation modulates the function of histone and non-histone proteins, and the enzymes that add or remove lysine methylation-lysine methyltransferases (KMTs) and lysine demethylases (KDMs), respectively-are frequently mutated and dysregulated...
7.
Chen Q, Bates A, Hanquier J, Simpson E, Rusch D, Podicheti R, et al.
J Biol Chem
. 2022 Apr;
298(5):101894.
PMID: 35378129
Extensive portions of the human genome have unknown function, including those derived from transposable elements. One such element, the DNA transposon Hsmar1, entered the primate lineage approximately 50 million years...
8.
Dickson B, Tiedemann R, Chomiak A, Cornett E, Vaughan R, Rothbart S
J Biol Chem
. 2020 Sep;
295(47):15826-15837.
PMID: 32994221
ChIP followed by next-generation sequencing (ChIP-Seq) is a key technique for mapping the distribution of histone posttranslational modifications (PTMs) and chromatin-associated factors across genomes. There is a perceived challenge to...
9.
Ledezma C, Cornett E, Kolpashchikov D
ACS Omega
. 2020 Mar;
5(8):4167-4171.
PMID: 32149246
We synthesized two dTTP analogues for copper-free "click" chemistry-coupling in the active sites of DNA polymerases. We found that in the presence of both analogues, human immunodeficiency virus (HIV) reverse...
10.
Colino-Sanguino Y, Cornett E, Moulder D, Smith G, Hrit J, Cordeiro-Spinetti E, et al.
iScience
. 2019 Nov;
21:773-788.
PMID: 31727574
Acetylation of the histone variant H2A.Z (H2A.Zac) occurs at active regulatory regions associated with gene expression. Although the Tip60 complex is proposed to acetylate H2A.Z, functional studies suggest additional enzymes...