Recent Progress in West Nile Virus Diagnosis and Vaccination

Overview

Journal Vet Res

Publisher Biomed Central

Specialty Veterinary Medicine

Date 2012 Mar 3

PMID 22380523

Citations 54

Authors

Marina De Filette

Sebastian Ulbert

Mike Diamond

Niek N Sanders

Affiliations

Soon will be listed here.

Abstract

West Nile virus (WNV) is a positive-stranded RNA virus belonging to the Flaviviridae family, a large family with 3 main genera (flavivirus, hepacivirus and pestivirus). Among these viruses, there are several globally relevant human pathogens including the mosquito-borne dengue virus (DENV), yellow fever virus (YFV), Japanese encephalitis virus (JEV) and West Nile virus (WNV), as well as tick-borne viruses such as tick-borne encephalitis virus (TBEV). Since the mid-1990s, outbreaks of WN fever and encephalitis have occurred throughout the world and WNV is now endemic in Africa, Asia, Australia, the Middle East, Europe and the Unites States. This review describes the molecular virology, epidemiology, pathogenesis, and highlights recent progress regarding diagnosis and vaccination against WNV infections.

Citing Articles

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