Generation and Characterization of an Advillin-Cre Driver Mouse Line

Overview

Journal Mol Pain

Date 2011 Sep 13

PMID 21906401

Citations 61

Authors

Sandra Zurborg

Agnieszka Piszczek

Conception Martinez

Philip Hublitz

Mumna Al Banchaabouchi

Pedro Moreira

Emerald Perlas

Paul A Heppenstall

Affiliations

Soon will be listed here.

Abstract

Progress in the somatosensory field has been restricted by the limited number of genetic tools available to study gene function in peripheral sensory neurons. Here we generated a Cre-driver mouse line that expresses Cre-recombinase from the locus of the sensory neuron specific gene Advillin. These mice displayed almost exclusive Cre-mediated recombination in all peripheral sensory neurons. As such, the Advillin-Cre-driver line will be a powerful tool for targeting peripheral neurons in future investigations.

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