Mikkeli Osteoporosis Index Identifies Fracture Risk Factors and Osteoporosis and Intervention Thresholds Parallel with FRAX

Overview

Journal J Osteoporos

Publisher Wiley

Specialty Orthopedics

Date 2011 Jul 21

PMID 21772977

Citations 1

Authors

Ville Juhana Waris

Joonas P Sirola

Vesa V Kiviniemi

Marjo T Tuppurainen

V Pekka Waris

Affiliations

Soon will be listed here.

Abstract

Osteoporosis Index (MOI) was developed from Fracture Index (FI), a validated fracture risk score, to identify also osteoporosis. MOI risk factors are age, weight, previous fracture, family history of hip fracture or spinal osteoporosis, smoking, shortening of the stature, and use of arms to rise from a chair. The association of these risk factors with BMD was examined in development cohorts of 300 Finnish postmenopausal women with a fracture and in a population control of 434 women aged 65-72. Validation cohorts included 200 fracture patients and a population control of 943 women aged 58-69. MOI identified femoral neck osteoporosis in these cohorts as well as the Osteoporosis Self-Assessment Tool (OST). In the pooled fracture cohort, the association of BMI-based FRAX fracture risk with MOI was good. After BMD measurement, MOI identified well FRAX hip fracture risk-based Intervention Thresholds (ITs) (AUC 0.74-0.90).

Citing Articles

Corrigendum to "Mikkeli Osteoporosis Index Identifies Fracture Risk Factors and Osteoporosis and Intervention Thresholds Parallel with FRAX".

Waris V, Sirola J, Kiviniemi V, Tuppurainen M, Waris V J Osteoporos. 2017; 2017:3074151.

PMID: 28913002 PMC: 5585658. DOI: 10.1155/2017/3074151.

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