» Articles » PMID: 21720303

Warfarin-related Nephropathy: Another Newly Recognized Complication of an Old Drug

Overview
Journal Kidney Int
Publisher Elsevier
Specialty Nephrology
Date 2011 Jul 2
PMID 21720303
Citations 15
Authors
Affiliations
Soon will be listed here.
Abstract

Since its approval in the 1950s, warfarin has been the most often prescribed anticoagulant, with attendant risks of bleeding. Brodsky et al. describe another potential complication of warfarin therapy. Warfarin-related nephropathy (WRN) has been described in patients with chronic kidney disease and appears to accelerate the rate of progression and increase the risk of death. The interactions between warfarin and chronic kidney disease are complex, and the recognition of the potential complications is expanding.

Citing Articles

Risk of mortality between warfarin and direct oral anticoagulants: population-based cohort studies.

Wang Z, Matthewman J, Tazare J, Yu Q, Cheung K, Chui C BMC Med. 2024; 22(1):597.

PMID: 39710653 PMC: 11664815. DOI: 10.1186/s12916-024-03808-y.


The impact of chronic kidney disease on prognosis in acute stroke: unraveling the pathophysiology and clinical complexity for optimal management.

Rajesh K, Spring K, Smokovski I, Upmanyue V, Mehndiratta M, Strippoli G Clin Exp Nephrol. 2024; 29(2):149-172.

PMID: 39627467 DOI: 10.1007/s10157-024-02556-w.


IgA Nephropathy Is the Most Common Underlying Disease in Patients With Anticoagulant-Related Nephropathy.

Trujillo H, Sandino J, Cavero T, Caravaca-Fontan F, Gutierrez E, Sevillano A Kidney Int Rep. 2022; 7(4):831-840.

PMID: 35497792 PMC: 9039479. DOI: 10.1016/j.ekir.2022.01.1048.


The Impairment in Kidney Function in the Oral Anticoagulation Era. A Pathophysiological Insight.

Scicchitano P, Tucci M, Bellino M, Cortese F, Cecere A, De Palo M Cardiovasc Drugs Ther. 2020; 35(3):505-519.

PMID: 32535717 DOI: 10.1007/s10557-020-07004-x.


Supratherapeutic International Normalized Ratio causing Nephropathy: A Rare Adverse Effect of Warfarin.

Rawala M, Ahmed A, Khan M, Riaz M, Eltoukhy A Cureus. 2019; 11(7):e5201.

PMID: 31565607 PMC: 6758983. DOI: 10.7759/cureus.5201.