A New Cytokine Receptor Superfamily

Overview

Journal Trends Biochem Sci

Specialty Biochemistry

Date 1990 Jul 1

PMID 2166365

Citations 102

Authors

D Cosman

S D Lyman

R L Idzerda

M P Beckmann

L S Park

R G Goodwin

C J March

Affiliations

Soon will be listed here.

Abstract

The amino acid sequences of several, recently cloned cytokine receptors show significant homologies, primarily in their extracellular, ligand-binding domains. With one exception, their cognate cytokines mediate biological activities on a variety of hematopoietic cell types; thus we have designated the receptors as the hematopoietic receptor superfamily.

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