Enhancement of Imaging Depth in Turbid Media Using a Wide Area Detector

Overview

Journal J Biophotonics

Date 2011 Mar 23

PMID 21425242

Citations 16

Authors

Viera Crosignani

Alexander S Dvornikov

Enrico Gratton

Affiliations

Soon will be listed here.

Abstract

The depth of two-photon fluorescence imaging in turbid media can be significantly enhanced by the use of the here described fluorescence detection method that allows to efficiently collect scattered fluorescence photons from a wide area of the turbid sample. By using this detector we were able to perform imaging of turbid samples, simulating brain tissue, at depths up to 3 mm, where the two-photon induced fluorescence signal is too weak to be detected by means used in conventional two-photon microscopy.

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