Universal Control Mechanism Regulating Onset of M-phase

Overview

Journal Nature

Specialty Science

Date 1990 Apr 5

PMID 2138713

Citations 850

Authors

P Nurse

Affiliations

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Abstract

The onset of M-phase is regulated by a mechanism common to all eukaryotic cells. Entry into M-phase is determined by activation of the p34cdc2 protein kinase which requires p34cdc2 dephosphorylation and association with cyclin.

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