Mitochondrial Transcription: How Does It End?

Overview

Journal Transcription

Specialty Molecular Biology

Date 2011 Feb 18

PMID 21326908

Citations 9

Authors

James Byrnes

Miguel Garcia-Diaz

Affiliations

Soon will be listed here.

Abstract

The structure of the mitochondrial transcription termination factor (MTERF1) provides novel insight into the mechanism of binding, recognition of the termination sequence and the conformational changes involved in mediating termination. Besides its functional implications, this structure provides a framework to understand the consequences of numerous diseases associated with mitochondrial DNA mutations.

Citing Articles

Mechanisms and regulation of human mitochondrial transcription.

Tan B, Gustafsson C, Falkenberg M Nat Rev Mol Cell Biol. 2023; 25(2):119-132.

PMID: 37783784 DOI: 10.1038/s41580-023-00661-4.

Mitochondrial Dynamics during Development.

He L, Tronstad K, Maheshwari A Newborn (Clarksville). 2023; 2(1):19-44.

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Mitofilin Heterozygote Mice Display an Increase in Myocardial Injury and Inflammation after Ischemia/Reperfusion.

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Structure, mechanism, and regulation of mitochondrial DNA transcription initiation.

Basu U, Bostwick A, Das K, Dittenhafer-Reed K, Patel S J Biol Chem. 2020; 295(52):18406-18425.

PMID: 33127643 PMC: 7939475. DOI: 10.1074/jbc.REV120.011202.

mTERF8, a Member of the Mitochondrial Transcription Termination Factor Family, Is Involved in the Transcription Termination of Chloroplast Gene .

Xiong H, Wang J, Huang C, Rochaix J, Lin F, Zhang J Plant Physiol. 2019; 182(1):408-423.

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