Fertility Preservation
Overview
Affiliations
Of the estimated 1.5 million men and women who were diagnosed as having cancer in 2010, approximately 10% are younger than 45 years. For these individuals, cancer treatment can be lifesaving but can permanently affect reproductive capacity. The American Society of Clinical Oncology has recommended that oncologists discuss the possibility of infertility with reproductive-age cancer patients and offer referral for fertility preservation consultation and therapy. Fertility preservation is an emerging field that offers treatment aimed at protecting future reproductive ability for individuals with cancer or other serious illnesses. Although fertility preservation strategies vary by patient age and sex, many allow patients to store gametes or reproductive tissues for potential future use to create offspring. As an emerging discipline, many questions remain about the role of fertility preservation. We performed a MEDLINE search from 1950 to June 2010 using the following MeSH terms: amenorrhea; antineoplastic agents; ovarian failure; premature; infertility, female; fertility preservation; infertility, male; adolescent and cancer; child and cancer; cryopreservation; and reproductive technologies, assisted. Studies considered for inclusion included those written in English and published before June 2010.
Affdal A, Salama M, Ravitsky V J Assist Reprod Genet. 2024; 41(4):999-1026.
PMID: 38430324 PMC: 11052756. DOI: 10.1007/s10815-024-03059-z.
Fath-Bayati L, Naserpour L, Khoshandam M, Jannatifar R, Fazaeli H Int J Reprod Biomed. 2023; 21(9):681-696.
PMID: 37969562 PMC: 10643686. DOI: 10.18502/ijrm.v21i9.14397.
Sperm Cryopreservation Today: Approaches, Efficiency, and Pitfalls.
Ozimic S, Ban-Frangez H, Stimpfel M Curr Issues Mol Biol. 2023; 45(6):4716-4734.
PMID: 37367049 PMC: 10296824. DOI: 10.3390/cimb45060300.
Roychoudhury S, Das A, Panner Selvam M, Chakraborty S, Slama P, Sikka S Front Cell Dev Biol. 2022; 10:877079.
PMID: 35646894 PMC: 9133602. DOI: 10.3389/fcell.2022.877079.
Stem cell-based therapies for fertility preservation in males: Current status and future prospects.
Liu H, Xie Y, Deng C, Liu G World J Stem Cells. 2020; 12(10):1097-1112.
PMID: 33178394 PMC: 7596443. DOI: 10.4252/wjsc.v12.i10.1097.