EUROCarbDB: An Open-access Platform for Glycoinformatics

Overview

Journal Glycobiology

Date 2010 Nov 26

PMID 21106561

Citations 40

Authors

Claus-Wilhelm von der Lieth

Ana Arda Freire

Dennis Blank

Matthew P Campbell

Alessio Ceroni

David R Damerell

Anne Dell

Raymond A Dwek

Beat Ernst

Rasmus Fogh

Martin Frank

Hildegard Geyer

Rudolf Geyer

Mathew J Harrison

Kim Henrick

Stefan Herget

William E Hull

John Ionides

Hiren J Joshi

Johannis P Kamerling

Bas R Leeflang

Thomas Lutteke

Magnus Lundborg

Kai Maass

Anthony Merry

Rene Ranzinger

Jimmy Rosen

Louise Royle

Pauline M Rudd

Siegfried Schloissnig

Roland Stenutz

Wim F Vranken

Goran Widmalm

Stuart M Haslam

Affiliations

Soon will be listed here.

Abstract

The EUROCarbDB project is a design study for a technical framework, which provides sophisticated, freely accessible, open-source informatics tools and databases to support glycobiology and glycomic research. EUROCarbDB is a relational database containing glycan structures, their biological context and, when available, primary and interpreted analytical data from high-performance liquid chromatography, mass spectrometry and nuclear magnetic resonance experiments. Database content can be accessed via a web-based user interface. The database is complemented by a suite of glycoinformatics tools, specifically designed to assist the elucidation and submission of glycan structure and experimental data when used in conjunction with contemporary carbohydrate research workflows. All software tools and source code are licensed under the terms of the Lesser General Public License, and publicly contributed structures and data are freely accessible. The public test version of the web interface to the EUROCarbDB can be found at http://www.ebi.ac.uk/eurocarb.

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