MicroRNAs in CNS Injury: Potential Roles and Therapeutic Implications

Overview

Journal Bioessays

Publisher Wiley

Specialties Biology
Cell Biology
Molecular Biology

Date 2010 Nov 6

PMID 21053309

Citations 34

Authors

Sindhu K Madathil

Peter T Nelson

Kathryn E Saatman

Bernard R Wilfred

Affiliations

Soon will be listed here.

Citing Articles

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Systematic Review of the Diagnostic and Clinical Utility of Salivary microRNAs in Traumatic Brain Injury (TBI).

Hiskens M, Mengistu T, Li K, Fenning A Int J Mol Sci. 2022; 23(21).

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Co-Expression Network Analysis of MicroRNAs and Proteins in Severe Traumatic Brain Injury: A Systematic Review.

Osgood C, Ahmed Z, Di Pietro V Cells. 2021; 10(9).

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Roles of miRNAs in spinal cord injury and potential therapeutic interventions.

Almurshidi B, Carver W, Scott G, Ray S Neuroimmunol Neuroinflamm. 2021; 6.

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Modulation of MicroRNAs as a Potential Molecular Mechanism Involved in the Beneficial Actions of Physical Exercise in Alzheimer Disease.

Improta-Caria A, Nonaka C, Cavalcante B, De Sousa R, Junior R, Souza B Int J Mol Sci. 2020; 21(14).

PMID: 32674523 PMC: 7403962. DOI: 10.3390/ijms21144977.

References

Wang W, Rajeev B, Stromberg A, Ren N, Tang G, Huang Q . The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1. J Neurosci. 2008; 28(5):1213-23. PMC: 2837363. DOI: 10.1523/JNEUROSCI.5065-07.2008. View

Uryu K, Giasson B, Longhi L, Martinez D, Murray I, Conte V . Age-dependent synuclein pathology following traumatic brain injury in mice. Exp Neurol. 2003; 184(1):214-24. DOI: 10.1016/s0014-4886(03)00245-0. View

Wang W, Wilfred B, Madathil S, Tang G, Hu Y, Dimayuga J . miR-107 regulates granulin/progranulin with implications for traumatic brain injury and neurodegenerative disease. Am J Pathol. 2010; 177(1):334-45. PMC: 2893676. DOI: 10.2353/ajpath.2010.091202. View

Smalheiser N, Lugli G . microRNA regulation of synaptic plasticity. Neuromolecular Med. 2009; 11(3):133-40. PMC: 3732454. DOI: 10.1007/s12017-009-8065-2. View

Uryu K, Chen X, Martinez D, Browne K, Johnson V, Graham D . Multiple proteins implicated in neurodegenerative diseases accumulate in axons after brain trauma in humans. Exp Neurol. 2007; 208(2):185-92. PMC: 3979356. DOI: 10.1016/j.expneurol.2007.06.018. View

McKee A, Gavett B, Stern R, Nowinski C, Cantu R, Kowall N . TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy. J Neuropathol Exp Neurol. 2010; 69(9):918-29. PMC: 2951281. DOI: 10.1097/NEN.0b013e3181ee7d85. View

Zhang X, Le W . Pathological role of hypoxia in Alzheimer's disease. Exp Neurol. 2009; 223(2):299-303. DOI: 10.1016/j.expneurol.2009.07.033. View

Copin J, Goodyear M, Gidday J, Shah A, Gascon E, Dayer A . Role of matrix metalloproteinases in apoptosis after transient focal cerebral ischemia in rats and mice. Eur J Neurosci. 2005; 22(7):1597-608. DOI: 10.1111/j.1460-9568.2005.04367.x. View

Bak M, Silahtaroglu A, Moller M, Christensen M, Rath M, Skryabin B . MicroRNA expression in the adult mouse central nervous system. RNA. 2008; 14(3):432-44. PMC: 2248253. DOI: 10.1261/rna.783108. View

10.

He Z, Ong C, Halper J, Bateman A . Progranulin is a mediator of the wound response. Nat Med. 2003; 9(2):225-9. DOI: 10.1038/nm816. View

11.

Yin K, Deng Z, Huang H, Hamblin M, Xie C, Zhang J . miR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia. Neurobiol Dis. 2010; 38(1):17-26. PMC: 2837803. DOI: 10.1016/j.nbd.2009.12.021. View

12.

Saatman K, Feeko K, Pape R, Raghupathi R . Differential behavioral and histopathological responses to graded cortical impact injury in mice. J Neurotrauma. 2006; 23(8):1241-53. DOI: 10.1089/neu.2006.23.1241. View

13.

Nelson P, Wang W, Rajeev B . MicroRNAs (miRNAs) in neurodegenerative diseases. Brain Pathol. 2008; 18(1):130-8. PMC: 2859437. DOI: 10.1111/j.1750-3639.2007.00120.x. View

14.

Redell J, Liu Y, Dash P . Traumatic brain injury alters expression of hippocampal microRNAs: potential regulators of multiple pathophysiological processes. J Neurosci Res. 2008; 87(6):1435-48. PMC: 5980641. DOI: 10.1002/jnr.21945. View

15.

Dharap A, Bowen K, Place R, Li L, Vemuganti R . Transient focal ischemia induces extensive temporal changes in rat cerebral microRNAome. J Cereb Blood Flow Metab. 2009; 29(4):675-87. PMC: 2743462. DOI: 10.1038/jcbfm.2008.157. View

16.

Liu N, Wang X, Lu Q, Xu X . Altered microRNA expression following traumatic spinal cord injury. Exp Neurol. 2009; 219(2):424-9. PMC: 2810508. DOI: 10.1016/j.expneurol.2009.06.015. View

17.

Friedman B, Schachtrup C, Tsai P, Shih A, Akassoglou K, Kleinfeld D . Acute vascular disruption and aquaporin 4 loss after stroke. Stroke. 2009; 40(6):2182-90. PMC: 2753985. DOI: 10.1161/STROKEAHA.108.523720. View

18.

Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere M . Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet. 2009; 41(10):1088-93. PMC: 2845877. DOI: 10.1038/ng.440. View

19.

Stozicka Z, Zilka N, Novak M . Risk and protective factors for sporadic Alzheimer's disease. Acta Virol. 2008; 51(4):205-22. View

20.

Nelson P, Wang W . MiR-107 is reduced in Alzheimer's disease brain neocortex: validation study. J Alzheimers Dis. 2010; 21(1):75-9. PMC: 2910235. DOI: 10.3233/JAD-2010-091603. View