Comparative Genome Analysis of Prevotella Ruminicola and Prevotella Bryantii: Insights into Their Environmental Niche

Overview

Journal Microb Ecol

Specialties Environmental Health
Microbiology

Date 2010 Jun 30

PMID 20585943

Citations 163

Authors

Janaki Purushe

Derrick E Fouts

Mark Morrison

Bryan A White

Roderick I Mackie

Pedro M Coutinho

Bernard Henrissat

Karen E Nelson

Affiliations

Soon will be listed here.

Abstract

The Prevotellas comprise a diverse group of bacteria that has received surprisingly limited attention at the whole genome-sequencing level. In this communication, we present the comparative analysis of the genomes of Prevotella ruminicola 23 (GenBank: CP002006) and Prevotella bryantii B(1)4 (GenBank: ADWO00000000), two gastrointestinal isolates. Both P. ruminicola and P. bryantii have acquired an extensive repertoire of glycoside hydrolases that are targeted towards non-cellulosic polysaccharides, especially GH43 bifunctional enzymes. Our analysis demonstrates the diversity of this genus. The results from these analyses highlight their role in the gastrointestinal tract, and provide a template for additional work on genetic characterization of these species.

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