» Articles » PMID: 2057998

Nuclear Gadgets in Mitochondrial DNA Replication and Transcription

Overview
Specialty Biochemistry
Date 1991 Mar 1
PMID 2057998
Citations 53
Authors
Affiliations
Soon will be listed here.
Abstract

In mammalian mitochondrial DNA, activation of the light-strand promoter mediates both priming of leading-strand replication and initiation of light-strand transcription. Accurate and efficient transcription requires at least two proteins: mitochondrial RNA polymerase and a separable transcription factor that can function across species boundaries. Subsequently, primer RNAs are cleaved by a site-specific ribonucleoprotein endoribonuclease that recognizes short, highly conserved sequence elements in the RNA substrate.

Citing Articles

Complete mitochondrial genome of and its phylogenetic status within the family Cobitidae (Cypriniformes).

Zhou M, Wang C, Xu Z, Peng Z, He Y, Wang Y Zookeys. 2024; 1221:51-69.

PMID: 39703235 PMC: 11653074. DOI: 10.3897/zookeys.1221.129136.


Comparative Mitogenomics Reveals Cryptic Species in McKay, 1985 (Perciformes: Sillaginidae).

Gao T, Shi Y, Xiao J Genes (Basel). 2023; 14(11).

PMID: 38002986 PMC: 10671150. DOI: 10.3390/genes14112043.


Characterization of the mitochondrial Huso huso genome and new aspects of its organization in the presence of tandem repeats in 12S rRNA.

Dadkhah K, Mianji G, Barzegar A, Farhadi A BMC Ecol Evol. 2023; 23(1):55.

PMID: 37749487 PMC: 10521412. DOI: 10.1186/s12862-023-02166-2.


Protein Transduction Domain-Mediated Delivery of Recombinant Proteins and In Vitro Transcribed mRNAs for Protein Replacement Therapy of Human Severe Genetic Mitochondrial Disorders: The Case of Sco2 Deficiency.

Miliotou A, Foltopoulou P, Ingendoh-Tsakmakidis A, Tsiftsoglou A, Vizirianakis I, Pappas I Pharmaceutics. 2023; 15(1).

PMID: 36678915 PMC: 9861957. DOI: 10.3390/pharmaceutics15010286.


Characterisation of the Complete Mitochondrial Genome of Critically Endangered (Carnivora: Mustelidae) and Its Phylogenetic and Conservation Implications.

Skorupski J Genes (Basel). 2022; 13(1).

PMID: 35052465 PMC: 8774856. DOI: 10.3390/genes13010125.