Assemble: an Interactive Graphical Tool to Analyze and Build RNA Architectures at the 2D and 3D Levels

Overview

Journal Bioinformatics

Publisher Oxford University Press

Specialty Biology

Date 2010 Jun 22

PMID 20562414

Citations 105

Authors

Fabrice Jossinet

Thomas E Ludwig

Eric Westhof

Affiliations

Soon will be listed here.

Abstract

Summary: Assemble is an intuitive graphical interface to analyze, manipulate and build complex 3D RNA architectures. It provides several advanced and unique features within the framework of a semi-automated modeling process that can be performed by homology and ab initio with or without electron density maps. Those include the interactive editing of a secondary structure and a searchable, embedded library of annotated tertiary structures. Assemble helps users with performing recurrent and otherwise tedious tasks in structural RNA research.

Availability And Implementation: Assemble is released under an open-source license (MIT license) and is freely available at http://bioinformatics.org/assemble. It is implemented in the Java language and runs on MacOSX, Linux and Windows operating systems.

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