Organizing Principles of Cortical Layer 6

Overview

Journal Front Neural Circuits

Date 2010 Feb 25

PMID 20179784

Citations 69

Authors

Farran Briggs

Affiliations

Soon will be listed here.

Abstract

Neurons in the deepest layer of mammalian cerebral cortex are morphologically and physiological diverse and are situated in a strategic position to modulate neuronal activity locally and in other structures. The variety of neuronal circuits within which layer 6 neurons participate differs across species and cortical regions. However even amidst this diversity, common organizational features emerge. Examination of the anatomical and physiological characteristics of different classes of layer 6 neuron, each specialized to participate in distinct circuits, provides insight into the functional contributions of layer 6 neurons toward cortical information processing.

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