A Tuning Method for Electrically Compensated Ion Cyclotron Resonance Mass Spectrometer Traps

Overview

Journal J Am Soc Mass Spectrom

Specialty Chemistry

Date 2010 Jan 12

PMID 20060743

Citations 3

Authors

Adam M Brustkern

Don L Rempel

Michael L Gross

Affiliations

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Abstract

We describe a method for tuning electrically compensated ion cyclotron resonance (ICR) traps by tracking the observed cyclotron frequency of an ion cloud at different oscillation mode amplitudes. Although we have used this method to tune the compensation voltages of a custom-built electrically compensated trap, the approach is applicable to other designs that incorporate electrical compensation. To evaluate the effectiveness of tuning, we examined the frequency shift as a function of cyclotron orbit size at different z-mode oscillation amplitudes. The cyclotron frequencies varied initially by approximately 12 ppm for ions with low z-mode oscillation amplitudes compared with those with high z-mode amplitudes. This frequency difference decreased to approximately 1 ppm by one iteration of trap tuning.

Citing Articles

A PERSPECTIVE ON PERSONAL CONTRIBUTIONS TO FT-ICR MASS SPECTROMETRY.

Gross M, Rempel D Mass Spectrom Rev. 2020; 41(2):178-193.

PMID: 32960989 PMC: 8888036. DOI: 10.1002/mas.21657.

Trapping radial electric field optimization in compensated FTICR cells.

Tolmachev A, Robinson E, Wu S, Smith R, Pasa-Toli L J Am Soc Mass Spectrom. 2011; 22(8):1334-42.

PMID: 21953187 DOI: 10.1007/s13361-011-0167-z.

Ion Behavior in an Electrically Compensated Ion Cyclotron Resonance Trap.

Brustkern A, Rempel D, Gross M Int J Mass Spectrom. 2011; 300(2-3):143-148.

PMID: 21499521 PMC: 3076697. DOI: 10.1016/j.ijms.2010.06.027.

References

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